十二碳-11-烯-1-醇合成路线 （共 31 条）
反应条件
ammonium chloride; iodine; magnesium; paraformaldehyde in tetrahydrofuran
参考文献
Cell Therapeutics, Inc.
Patent: US5521315 A1, 1996 ;
反应条件
lithium aluminium tetrahydride
参考文献
Kato, Minoru; Mori, Kenji
Agricultural and Biological Chemistry, 1985 , vol. 49, # 8 p. 2479 - 2480
反应条件
hexadecanoic acid; octadecanoic acid T=350°C; P=260 Torr;
参考文献
Zakharkin, L. I.; Guseva, V. V.
Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 733 - 736
Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 776 - 779
反应条件
potassium tert-butylate in tetrahydrofuran T=20°C;
参考文献
Csuk, Rene; Niesen, Anja
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2004 , vol. 59, # 8 p. 934 - 942
反应条件
potassium hydroxide in methanol; water 8 h; Heating;
参考文献
Zakharkin, L. I.; Guseva, V. V.
Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 733 - 736
Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 776 - 779
反应条件
sodium tetrahydroborate; mercury(II) diacetate; water; potassium carbonate 1.) THF, 0 deg C to r.t., 25 min, 2.) THF, 0 deg C to r.t., 30 min; Yield givenMultistep reaction;
参考文献
Gebauer, Julian; Blechert, Siegfried
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 2021 - 2025
反应条件
1: tetrahydrofuran 2: Hg(OAc)2; NaBH4 / methanol View Scheme
参考文献
Gebauer, Julian; Blechert, Siegfried
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 2021 - 2025
反应条件
1: 81 percent / Et3N / CH2Cl2 / 3 h / 0 °C 2: 98 percent / dimethylsulfoxide / 0.17 h / 80 °C 3: 67 percent / 25percent aq. NaOH / methanol / 24 h / Heating 4: 60 percent / LiAlH4 / tetrahydrofuran / 16 h / Ambient temperature View Scheme
参考文献
O'Brien; Sliskovic; Picard; Lee; Purchase II; Roth; White; Anderson; Mueller; Bocan; Bousley; Hamelehle; Homan; Krause; Reindel; Stanfield; Turluck
Journal of Medicinal Chemistry, 1996 , vol. 39, # 12 p. 2354 - 2366
反应条件
1: 67 percent / 25percent aq. NaOH / methanol / 24 h / Heating 2: 60 percent / LiAlH4 / tetrahydrofuran / 16 h / Ambient temperature View Scheme
参考文献
Kato, Minoru; Mori, Kenji
Agricultural and Biological Chemistry, 1985 , vol. 49, # 8 p. 2479 - 2480
反应条件
1: 98 percent / dimethylsulfoxide / 0.17 h / 80 °C 2: 67 percent / 25percent aq. NaOH / methanol / 24 h / Heating 3: 60 percent / LiAlH4 / tetrahydrofuran / 16 h / Ambient temperature View Scheme
参考文献
O'Brien; Sliskovic; Picard; Lee; Purchase II; Roth; White; Anderson; Mueller; Bocan; Bousley; Hamelehle; Homan; Krause; Reindel; Stanfield; Turluck
Journal of Medicinal Chemistry, 1996 , vol. 39, # 12 p. 2354 - 2366
