1-乙基-3-甲基-1H-吡唑-5-胺合成路线 （共 5 条）
反应条件
hydrazine hydrate in butan-1-ol; benzene
反应条件
in ethanol 4 h; Reflux;
参考文献
BRACCO IMAGING S.P.A.; SWENSON, Rolf, E.; RAJU, Natarajan; ESTRELLA-JIMENEZ, Maria, E.; RAMALINGAM, Kondareddiar
Patent: WO2011/159864 A1, 2011 ;
Location in patent: Page/Page column 47-48 ;
参考文献
Tret'yakov; Vasilevsky
Russian Chemical Bulletin, 1996 , vol. 45, # 11 p. 2585 - 2587
反应条件
1: 120 °C
2: POCl3 / 120 °C
3: aq. KOH / 1,2-dimethoxy-ethane / 20 °C
View Scheme
参考文献
Ochiai, Hiroshi; Ishida, Akiharu; Ohtani, Tazumi; Kusumi, Kensuke; Kishikawa, Katuya; Yamamoto, Susumu; Takeda, Hiroshi; Obata, Takaaki; Nakai, Hisao; Toda, Masaaki
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 9 p. 1098 - 1104
反应条件
1: 120 °C
2: POCl3 / 120 °C
View Scheme
参考文献
Ochiai, Hiroshi; Ishida, Akiharu; Ohtani, Tazumi; Kusumi, Kensuke; Kishikawa, Katuya; Yamamoto, Susumu; Takeda, Hiroshi; Obata, Takaaki; Nakai, Hisao; Toda, Masaaki
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 9 p. 1098 - 1104
