4-溴甲基-7-甲氧基香豆素合成路线 (共 12 条)
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 8 h; Reflux;
参考文献
Belluti, Federica; Fontana, Gabriele; Bo, Laura Dal; Carenini, Nives; Giommarelli, Chiara; Zunino, Franco
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 10 p. 3543 - 3550
反应条件
aluminium trichloride in nitrobenzene T=20°C; 3 h;
参考文献
Kimura, Hitoshi; Sato, Hirotoshi; Tsuchiya, Chizuko; Chiba, Takuo; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 552 - 558
反应条件
1: sulfuric acid 2: acetone; potassium carbonate View Scheme
参考文献
Journal of Scientific and Industrial Research, , vol. 11 B, p. 39,43
反应条件
potassium carbonate; acetone
参考文献
Journal of Scientific and Industrial Research, , vol. 11 B, p. 39,43
反应条件
bromine; acetic acid
参考文献
Journal of the Indian Chemical Society, , vol. 11, p. 635,648
反应条件
potassium carbonate in ethanol 5 h; Heating;
参考文献
Hanmantgad, Shrikant S.; Kulkarni, Manohar V.; Patil, Vemanna D.; Diwan, Prakash V.; Kulkarni, Dhruvaraj R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 779 - 781
反应条件
potassium carbonate in ethanol 5 h; Heating;
参考文献
Hanmantgad, Shrikant S.; Kulkarni, Manohar V.; Patil, Vemanna D.; Diwan, Prakash V.; Kulkarni, Dhruvaraj R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 779 - 781
反应条件
ammonium hydroxide in water; acetone T=20°C; 1 h;
参考文献
Onderwater, Rob C. A.; Venhorst, Jennifer; Commandeur, Jan N. M.; Vermeulen, Nico P. E.
Chemical Research in Toxicology, 1999 , vol. 12, # 7 p. 555 - 559
反应条件
1: With sodium hydroxide in water 6 h; Heating / reflux; 2: With hydrogenchloride in water T=0°C;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1717238 A1, 2006 ;
Location in patent: Page/Page column 52 ;
反应条件
1: silver acetate
2: aq.-ethanolic hydrochloric acid
View Scheme
参考文献
Sehgal; Seshadri
Journal of Scientific and Industrial Research, 1953 , vol. 12 B, p. 346,348