triethylamine T=0°C;

暂无反应条件数据

1: carbonic acid chloromethyl ester isopropyl ester; (R)-9-[2-(phosphonomethoxy)propyl]adenine With chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide in 1-methyl-pyrrolidin-2-one T=50 - 55°C; 5 h; 2: (2E)-but-2-enedioic acid in isopropyl alcohol T=50°C;

1.1: chloro-trimethyl-silane; triethylamine; tetrabutylammomium bromide / N-methyl-pyrrolidine / 50 - 55 °C 1.2: 5 h / 50 - 55 °C 2.1: isopropyl alcohol / 50 °C View Scheme

sodium hydrogencarbonate; sodium iodide in acetone

in benzene a.) RT, 1 h, b.) reflux, 1 h;

in benzene a.) RT, 1 h, b.) reflux, 1 h;