(5-甲基异恶唑-3-基)甲醇合成路线 （共 17 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78 - 20°C; Oxidation; 0.25 h;
参考文献
Khanna; Yu; Huff; Weier; Xu; Koszyk; Collins; Cogburn; Isakson; Koboldt; Masferrer; Perkins; Seibert; Veenhuizen; Yuan; Yang; Zhang
Journal of Medicinal Chemistry, 2000 , vol. 43, # 16 p. 3168 - 3185
反应条件
potassium dichromate; sulfuric acid
参考文献
Quilico; Panizzi
Gazzetta Chimica Italiana, 1939 , vol. 69, p. 536,541
反应条件
1: 65 percent / Ph3PBr2 / CH2Cl2 / 1 h / Ambient temperature 2: 84 percent / NaN3 / acetone / 24 h / Ambient temperature View Scheme
参考文献
Pei; Wickhan
Tetrahedron Letters, 1993 , vol. 34, # 47 p. 7509 - 7512
反应条件
1: 65 percent / Ph3PBr2 / CH2Cl2 / 1 h / Ambient temperature 2: 84 percent / NaN3 / acetone / 24 h / Ambient temperature 3: 98 percent / NaBH4, TEA / HS(CH2)3SH / propan-2-ol / 24 h / Ambient temperature View Scheme
参考文献
Pei; Wickhan
Tetrahedron Letters, 1993 , vol. 34, # 47 p. 7509 - 7512
反应条件
PPh3.Br2 in dichloromethane 1 h; Ambient temperature;
参考文献
Pei; Wickhan
Tetrahedron Letters, 1993 , vol. 34, # 47 p. 7509 - 7512
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl acetamide T=150°C; 16 h; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 352, # 4 p. 696 - 710
反应条件
(i) nBuLi, THF, hexane, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Gainer,J. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 994 - 997
