5-氯-2-(甲硫基)苯并噻唑合成路线 （共 10 条）
反应条件
sodium hydroxide T=20°C; 1 h;
参考文献
COMPOUND HANDLING B.V.; STICHTING KATHOLIEKE UNIVERSITEIT; HOOIJ, VAN, Onno; SCHALKEN, Jacobus Antonius; VIËTOR, Hendrik Engelbertus; PIET, Dennis Patrick; MAAS, Petrus Emmanuel Marie; TIJHUIS, Johann Heinrich; DEERENBERG, Sirik; SPRENKELS, Nanda Elisabeth; TANG, Siu Ha
Patent: WO2013/131931 A1, 2013 ;
Location in patent: Page/Page column 29; 30 ;
反应条件
1: 0.08 h / Microwave irradiation 2: N-ethyl-N,N-diisopropylamine / acetone / 20 °C / Sonication View Scheme
参考文献
Journal of Photochemistry and Photobiology B: Biology, , vol. 103, # 3 p. 215 - 221
反应条件
1: potassium hydroxide / ethanol; water / Reflux 2: sodium hydroxide / 1 h / 20 °C View Scheme
参考文献
Chemistry and Biodiversity, , vol. 8, # 2 p. 253 - 265
参考文献
Journal of the Chemical Society, , p. 470,473
参考文献
Journal of the Chemical Society, , p. 3311,3314
反应条件
hydrazine hydrate in ethanol T=100°C; 3 h; Inert atmosphere;
参考文献
COMPOUND HANDLING B.V.; STICHTING KATHOLIEKE UNIVERSITEIT; HOOIJ, VAN, Onno; SCHALKEN, Jacobus Antonius; VIËTOR, Hendrik Engelbertus; PIET, Dennis Patrick; MAAS, Petrus Emmanuel Marie; TIJHUIS, Johann Heinrich; DEERENBERG, Sirik; SPRENKELS, Nanda Elisabeth; TANG, Siu Ha
Patent: WO2013/131931 A1, 2013 ;
Location in patent: Page/Page column 30 ;
反应条件
methyl 4-toluenesulfonate Behandeln des Reaktionsprodukts mit wss. NaOH;
参考文献
Hoggarth
Journal of the Chemical Society, 1949 , p. 3311,3314
反应条件
1: KMnO4; aqueous acetic acid 2: aq.-ethanolic HCl View Scheme
参考文献
Hoggarth
Journal of the Chemical Society, 1949 , p. 3311,3314
反应条件
iodine
T=200 - 210°C;
参考文献
Logemann,W. et al.
Farmaco, Edizione Scientifica, 1961 , vol. 16, p. 795 - 816
反应条件
Behandeln des Reaktionsprodukts mit wss. NaHS;
参考文献
Sexton
Journal of the Chemical Society, 1939 , p. 470,473
