3-二甲基氨基-1-苯丙烷-1-酮合成路线 (共 69 条)
反应条件
chloromethyl iodide in dimethyl sulfoxide 3 h; Ambient temperature;
参考文献
Miyano, Sotaro; Hokari, Hiroshi; Mori, Akira; Hashimoto, Harukichi
Chemistry Letters, 1980 , p. 1213 - 1214
反应条件
sodium iodide in diethyl ether 48 h; Reflux;
参考文献
Kosmalski, Tomasz
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 6 p. 717 - 721
反应条件
acetic acid in acetonitrile Mannich reaction; 12 h; Reflux;
参考文献
Guo, Yuan; An, Jing; Lu, Zhenhuan; Peng, Mengjiao
Chinese Journal of Chemistry, 2012 , vol. 30, # 7 p. 1561 - 1564
反应条件
in dichloromethane Boron enolate in CH2Cl2 is treated with 1.5 equivalents of TMDM at 0°C, stirring for 2 h at room temp.; distillation;
参考文献
Nolen, Ernest G.; Allocco, Andrea; Vitarius, Jim; McSorley, Karen
Journal of the Chemical Society, Chemical Communications, 1990 , # 21 p. 1532 - 1533
反应条件
in acetonitrile T=80°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 8 p. 2691 - 2695
参考文献
Chemische Berichte, , vol. 66, p. 418
反应条件
hydrogenchloride; water
参考文献
Archiv der Pharmazie (Weinheim, Germany), , p. 746
反应条件
1: dioxane 2: aqueous sulfuric acid View Scheme
参考文献
Chemische Berichte, , vol. 66, p. 418
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 271, p. 101,113
反应条件
in acetonitrile T=25°C; Rate constantMechanism;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 22, # 7 p. 1299 - 1302
Zhurnal Organicheskoi Khimii, , vol. 22, # 7 p. 1442 - 1446