3-(4-甲酰基苯基)丙酸合成路线 （共 12 条）
反应条件
hydrogen; platinum(IV) oxide in ethyl acetate T=25°C; P=750.075 Torr; 0.666667 h;
参考文献
The Scripps Research Institute
Patent: US2005/26987 A1, 2005 ;
Location in patent: Page 30 ;
反应条件
manganese(IV) oxide in dichloromethane T=35°C; 18 h;
参考文献
CHROMA THERAPEUTICS LTD.
Patent: WO2008/40934 A1, 2008 ;
Location in patent: Page/Page column 82 ;
WO 2008/040934 A1
反应条件
lithium hydroxide; water in tetrahydrofuran T=50°C; 3 h;
参考文献
Giannini, Giuseppe; Marzi, Mauro; Pezzi, Riccardo; Brunetti, Tiziana; Battistuzzi, Gianfranco; Marzo, Maria Di; Cabri, Walter; Vesci, Loredana; Pisano, Claudio
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 8 p. 2346 - 2349
反应条件
1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=50 - 80°C;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
oxoammonium salt in water; acetonitrile T=20°C; 8 h;
参考文献
Qiu, Joseph C.; Pradhan, Priya P.; Blanck, Nyle B.; Bobbitt, James M.; Bailey, William F.
Organic Letters, 2012 , vol. 14, # 1 p. 350 - 353
反应条件
hydrogenchloride in 1,4-dioxane; dichloromethane; palladium
参考文献
Hoffmann-La Roche Inc.
Patent: US3969373 A1, 1976 ;
反应条件
manganese(IV) dioxide in ethanol
反应条件
1: With N-chloro-succinimide; diethylamine in dichloromethane Inert atmosphereCooling with ice; 2: With 2-pentafluorophenyl-6,17dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; water; triethylamine in dichloromethane T=20°C; 7 h; Inert atmosphere; chemoselective reaction;
参考文献
Kuwano, Satoru; Harada, Shingo; Oriez, Raphael; Yamada, Ken-Ichi
Chemical Communications, 2012 , vol. 48, # 1 p. 145 - 147
反应条件
palladium Hydrogenation;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 141, p. 44,57
反应条件
in methanol; sodium hydroxide
