borane-THF; boron trifluoride diethyl etherate in tetrahydrofuran T=20°C; 18 h;

lithium diisopropyl amide in tetrahydrofuran T=-85°C; 0.05 h;

1: 3-amino-benzyl alcohol With hydrogenchloride in water T=0°C; 0.0833333 h; Inert atmosphereSchlenk technique; 2: With tert.-butylnitrite T=0°C; 0.25 h; Inert atmosphereSchlenk technique; 3: trifluoromethylsilver T=-78 - 20°C; 4 h; Inert atmosphereSchlenk technique;

copper; sodium hydrogencarbonate in N,N-dimethyl-formamide T=50°C; 11 h; Sealed tube;

chromium dichloride; lithium iodide in tetrahydrofuran T=55°C; Hiyama-Nozaki reaction; 3 h;

1: 57 percent Spectr. / iodosylbenzene; 1,1,1,3,3,3-hexafluoro-2-propanol; aq. HBF4 / CH2Cl2 / 8 h / 20 °C 2: NaBH4 / methanol / 1 h / 20 °C View Scheme

1: 69 percent Spectr. / hydroxy(phenyl)(tetrafluoroborato)-λ3-iodane; 1,1,1,3,3,3-hexafluoro-2-propanol / CH2Cl2; H2O / 6 h / 20 °C 2: NaBH4 / methanol / 1 h / 20 °C View Scheme

formaldehyd; diethyl ether unter Stickstoff;

water; sodium carbonate

glucose dehydrogenase; β-D-glucopyranose; beta-nicotinamide adeninedinucleotide phosphatedisodium salt; catalase from Micrococcus lysodeikticus; cytochrome P450 BM3 monooxygenase from Bacillus megaterium F87A, L188C double mutant; potassium chloride; oxygen; tris(hydroxymethyl)methylamine hydrochloride in aq. phosphate buffer; dimethyl sulfoxide T=30°C; pH=7.5; 24 h; Green chemistryEnzymatic reaction; Reagent/catalyst; regioselective reaction;