3,5-二(三氟甲基)苯甲醚合成路线 （共 9 条）
反应条件
18-crown-6 ether; copper(I) bromide in methanol T=105°C; 22 h;
参考文献
MEUDT, Andreas; Rausch, Bernhard J.
Patent: US2008/71084 A1, 2008 ;
Location in patent: Page/Page column 4 ;
反应条件
sulfur(IV) fluoride; hydrogen fluoride T=140°C; 20 h;
参考文献
Dmowski, Wojciech; Piasecka-Maciejewska, Krystyna
Journal of Fluorine Chemistry, 1996 , vol. 81, # 1 p. 59 - 63
参考文献
Journal of the American Chemical Society, , vol. 69, p. 946
Industrial and Engineering Chemistry, , vol. 39, p. 421
反应条件
potassium hydroxide 1.) MeOH, 2.) THF, room temp., overnight; reflux, 3 h;
参考文献
Dmowski, Wojciech; Piasecka-Maciejewska, Krystyna
Journal of Fluorine Chemistry, 1996 , vol. 81, # 1 p. 59 - 63
反应条件
1: 52 percent / HF, SF4 / 20 h / 60 °C 2: 82 percent / KOH / 1.) MeOH, 2.) THF, room temp., overnight; reflux, 3 h View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 81, # 1 p. 59 - 63
反应条件
1: KOH / tetrahydrofuran / 1.) room temp., overnight, 2.) reflux, 3 h 2: 95.6 percent / aq. KOH / Heating 3: 83 percent / HF, SF4 / 20 h / 140 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 81, # 1 p. 59 - 63
反应条件
potassium hydroxide in N,N-dimethyl-formamide
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 34, # 7 p. 2250 - 2254,2262 - 2265
反应条件
1: 95.6 percent / aq. KOH / Heating 2: 83 percent / HF, SF4 / 20 h / 140 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 81, # 1 p. 59 - 63
反应条件
n-butyllithium in diethyl ether 2 h; Ambient temperature;
参考文献
Dmowski, Wojciech; Piasecka-Maciejewska, Krystyna
Journal of Fluorine Chemistry, 1996 , vol. 81, # 1 p. 59 - 63
