3-溴-4-甲氧基苯甲醛合成路线 （共 37 条）
反应条件
1.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 - 0 °C / |Inert atmosphere 2.1: oxalyl dichloride; dimethyl sulfate / dichloromethane / 1 h / -78 °C / |Inert atmosphere 2.2: 2 h / -78 - 20 °C / |Inert atmosphere View Scheme
参考文献
Tetrahedron, , vol. 69, # 13 p. 2807 - 2815
反应条件
1.1: CH3BF3(1-)*H(1+)*C4H10O; N-bromosuccinmide / acetonitrile / 23 h / -10 - 20 °C / |Inert atmosphere 2.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 - 0 °C / |Inert atmosphere 3.1: oxalyl dichloride; dimethyl sulfate / dichloromethane / 1 h / -78 °C / |Inert atmosphere 3.2: 2 h / -78 - 20 °C / |Inert atmosphere View Scheme
参考文献
Tetrahedron, , vol. 69, # 13 p. 2807 - 2815
反应条件
1.1: potassium carbonate / acetone / 4 h / |Inert atmosphere; |Reflux 2.1: CH3BF3(1-)*H(1+)*C4H10O; N-bromosuccinmide / acetonitrile / 23 h / -10 - 20 °C / |Inert atmosphere 3.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 - 0 °C / |Inert atmosphere 4.1: oxalyl dichloride; dimethyl sulfate / dichloromethane / 1 h / -78 °C / |Inert atmosphere 4.2: 2 h / -78 - 20 °C / |Inert atmosphere View Scheme
参考文献
Tetrahedron, , vol. 69, # 13 p. 2807 - 2815
反应条件
bromine in dichloromethane; water T=20°C; Oxidation; bromination; 5 h; Irradiation; Product distribution; Further Variations:Solvents;
参考文献
Journal of Organic Chemistry, , vol. 65, # 12 p. 3880 - 3881
反应条件
water in 1,4-dioxane T=34°C; Kinetics;
参考文献
Tetrahedron Letters, , vol. 23, # 12 p. 1305 - 1308
反应条件
1: diluted nitric acid 2: bromine View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 56, p. 308
Annales de Chimie (Cachan, France), , vol. <3> 14, p. 486
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 11 p. 1797 - 1802
反应条件
sodium hypochlorite; tetrabutylammomium bromide in ethyl acetate T=20°C; 2.5 h;
参考文献
Leduc, Andrew B.; Jamison, Timothy F.
Organic Process Research and Development, 2012 , vol. 16, # 5 p. 1082 - 1089
反应条件
sodium tetrahydroborate; ethanol in water T=0 - 20°C;
参考文献
Odlo, Kristin; Fournier-Dit-Chabert, Jeremie; Ducki, Sylvie; Gani, Osman A.B.S.M.; Sylte, Ingebrigt; Hansen, Trond Vidar
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6874 - 6885
反应条件
hydrogenchloride; sodium hydroxide in ethyl acetate; tert-butyl alcohol
参考文献
Japan Tobacco Inc.
Patent: US6017919 A1, 2000 ;
