CBZ-L-天门冬氨酸β-苄酯合成路线 （共 20 条）
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran 0.0833333 h; Ambient temperature;
参考文献
McGeary, Ross P.
Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3319 - 3322
反应条件
1: N,N-diisopropylethylamine (DIPEA) / tetrahydrofuran / 0.08 h / Ambient temperature 2: NaBH4 / tetrahydrofuran / 0.33 h / Ambient temperature 3: p-TsOH / benzene / Heating View Scheme
参考文献
Rodriguez; Llinares; Doulut; Heitz; Martinez
Tetrahedron Letters, 1991 , vol. 32, # 7 p. 923 - 926
参考文献
Berger; Katchalski
Journal of the American Chemical Society, 1951 , vol. 73, p. 4084,4087
反应条件
hydrogen bromide; acetic acid
参考文献
Ben-Ishai; Berger
Journal of Organic Chemistry, 1952 , vol. 17, p. 1564,1565
反应条件
lithium aluminium tetrahydride; chloroformic acid ethyl ester
参考文献
Sato, Toshio; Goto, Yoshihiko; Fujisawa, Tamotsu
Tetrahedron Letters, 1982 , vol. 23, # 40 p. 4111 - 4112
反应条件
dichloromethane; triethylamine; dicyclohexyl-carbodiimide
参考文献
Bryant et al.
Journal of the Chemical Society, 1959 , p. 3868,3870
反应条件
triethylamine; phosphorochloridic acid diphenyl ester in ethyl acetate
24 h; Ambient temperature;
参考文献
Poechlauer, Peter; Hendel, Wolfram
Tetrahedron, 1998 , vol. 54, # 14 p. 3489 - 3494
反应条件
triethylamine; dicyclohexyl-carbodiimide in dichloromethane
参考文献
Anderson; Barton; Hardy; Kenner; Preston; Sheppard
Journal of the Chemical Society. Perkin transactions 1, 1967 , vol. 1, p. 108 - 113
反应条件
1: 79.3 percent / DCC / dimethylformamide / 4 °C
2: 92.5 percent / dioxane / Ambient temperature
View Scheme
参考文献
Tsuboi; Okada
Chemical and pharmaceutical bulletin, 1989 , vol. 37, # 1 p. 46 - 49
参考文献
Swallow et al.
Biochemical Journal, 1958 , vol. 70, p. 359,361
