4-氯-1,2-苯异噻唑-3-酮-1,1-二氧化物合成路线 （共 4 条）
反应条件
sulfuric acid T=20°C; 1.5 h;
参考文献
PIERRE FABRE MEDICAMENT; PEREZ, Michel; LAMOTHE, Marie; JUNQUERO, Didier; RIVAL, Yves
Patent: WO2010/100139 A1, 2010 ;
Location in patent: Page/Page column 33 ;
WO 2010/100139 A1
反应条件
chromium(VI) oxide; periodic acid in acetonitrile 1 h; Heating;
参考文献
Xu, Liang; Shu, Hong; Liu, Ying; Zhang, Suhong; Trudell, Mark L.
Tetrahedron, 2006 , vol. 62, # 33 p. 7902 - 7910
反应条件
ammonium hydroxide in tetrahydrofuran T=10 - 20°C; 1 h;
参考文献
Xu, Liang; Trudell, Mark L.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 435 - 438
反应条件
1.1: aq. sodium nitrite; aq. hydrochloric acid / 0.75 h / 0 °C 1.2: 27.5 g / sulfur dioxide; aq. acetic acid; copper(I) chloride / 1 h / 0 °C 2.1: 17.3 g / concd. ammonium hydroxide / tetrahydrofuran / 1 h / 10 - 20 °C View Scheme
参考文献
Xu, Liang; Trudell, Mark L.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 435 - 438
