1-甲基-2-苯基-1H-咪唑合成路线 （共 22 条）
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide in toluene T=20°C; 0.25 h;
参考文献
Debdab, Mansour; Mongin, Florence; Bazureau, Jean Pierre
Synthesis, 2006 , # 23 p. 4046 - 4052
反应条件
copper(l) iodide; 1,10-phenanthroline; Et3CoLi in N,N'-dimethyl-N,N'-propyleneurea T=125°C; 12 h; Inert atmosphere;
参考文献
Do, Hien-Quang; Khan, Rana M. Kashif; Daugulis, Olafs
Journal of the American Chemical Society, 2008 , vol. 130, # 45 p. 15185 - 15192
反应条件
[(2-phenylpyridine(-H))2IrIII(2,2′-bipyridine)]PF6 T=20°C; 16 h; Inert atmosphereIrradiation;
参考文献
Tobisu, Mamoru; Furukawa, Takayuki; Chatani, Naoto
Chemistry Letters, 2013 , vol. 42, # 10 p. 1203 - 1205
反应条件
bis-triphenylphosphine-palladium(II) chloride in xylene T=120°C; 20 h;
参考文献
Kosugi, Masanori; Koshiba, Mamoru; Atoh, Akira; Sano, Hiroshi; Migita, Toshihiko
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 2 p. 677 - 679
反应条件
NaH in tetrahydrofuran; water; ethyl acetate
参考文献
SOLVAY (SOCIETE ANONYME)
Patent: US2010/102711 A1, 2010 ;
反应条件
dimethyl sulfate; lithium diisopropyl amide in tetrahydrofuran
参考文献
Neurogen Corporation, Corporation of the State of Delaware
Patent: US2003/18025 A1, 2003 ;
US 20030018025 A1
反应条件
selenium in dichloromethane T=16°C; 72 h; Inert atmosphere;
参考文献
Marchenko, Anatolii P.; Koidan, Heorgii N.; Huryeva, Anastasiya N.; Zarudnitskii, Evgeniy V.; Yurchenko, Aleksandr A.; Kostyuk, Aleksandr N.
Journal of Organic Chemistry, 2010 , vol. 75, # 21 p. 7141 - 7145
反应条件
lithium diisopropyl amide in tetrahydrofuran; hexane T=20°C; 3 h; Inert atmosphere; regioselective reaction;
参考文献
Truong, Thanh; Daugulis, Olafs
Journal of the American Chemical Society, 2011 , vol. 133, # 12 p. 4243 - 4245
反应条件
1: in diethyl ether T=-30 - 16°C; Inert atmosphere; 2: With sulfur in diethyl ether 0.25 h; HeatingInert atmosphere;
参考文献
Marchenko, Anatolii P.; Koidan, Heorgii N.; Huryeva, Anastasiya N.; Zarudnitskii, Evgeniy V.; Yurchenko, Aleksandr A.; Kostyuk, Aleksandr N.
Journal of Organic Chemistry, 2010 , vol. 75, # 21 p. 7141 - 7145
反应条件
tetrabutylammomium bromide; copper diacetate; palladium diacetate in 1,4-dioxane; dimethyl sulfoxide T=20 - 110°C; 24.08 h; Inert atmosphere;
参考文献
Liu, Bo; Guo, Qiang; Cheng, Yangyang; Lan, Jingbo; You, Jingsong
Chemistry - A European Journal, 2011 , vol. 17, # 48 p. 13415 - 13419
