2-(4-溴苯氧基)乙醇合成路线 （共 18 条）
反应条件
sodium hydroxide T=20°C; 24 h;
参考文献
Inokuma, Seiichi; Kimura, Koichi; Funaki, Takashi; Nishimura, Jun
Heterocycles, 2001 , vol. 54, # 1 p. 123 - 130
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 72 h;
参考文献
Gegout, Aline; Delgado, Juan Luis; Nierengarten, Jean-Franois; Delavaux-Nicot, Beatrice; Listorti, Andrea; Chiorboli, Claudio; Belbakra, Abdelhalim; Armaroli, Nicola
New Journal of Chemistry, 2009 , vol. 33, # 10 p. 2174 - 2182
反应条件
1H-imidazole in xylenes T=140°C; 72 h;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2007/88514 A1, 2007 ;
Location in patent: Page/Page column 42 ;
WO 2007/088514 A1
反应条件
1: 4-bromo-phenol With sodium hydroxide in ethanol T=70°C; 0.5 h; 2: 2-bromo-1-ethanol in ethanol T=70°C; Heating / reflux;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2006/79988 A1, 2006 ;
Location in patent: Page/Page column 9; 14 ;
WO 2006/079988 A1
反应条件
1: With sodium acetate in water; acetic acid T=15°C; 2: With bromine in water; acetic acid T=10 - 20°C; 0.5 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1184381 A1, 2002 ;
Location in patent: Page 37 ;
反应条件
potassium hydroxide in dimethyl sulfoxide T=80°C; 0.166667 h; Microwave irradiation;
参考文献
Pothi, Tejas; Dawange, Mahesh; Chavan, Kamlesh; Sharma, Rajiv; Deka, Nabajyoti
Journal of the Korean Chemical Society, 2012 , vol. 56, # 6 p. 706 - 711
反应条件
sodium tetrahydroborate in ethanol T=0 - 20°C;
参考文献
Twibanire, Jean-D'Amour K.; Al-Mughaid, Hussein; Grindley, T. Bruce
Tetrahedron, 2010 , vol. 66, # 50 p. 9602 - 9609
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1462
反应条件
n-dodecyl sulfate; bromine in water 48 h; Yields of byproduct given;
参考文献
Tetrahedron, , vol. 44, # 5 p. 1553 - 1558
反应条件
pyridine; thionyl chloride in toluene T=20°C; 2 h; RefluxDean-Stark;
参考文献
Ace, Karl W.; Armitage, Mark A.; Bellingham, Richard K.; Blackler, Paul D.; Ennis, David S.; Hussain, Nigel; Lathbury, David C.; Morgan, David O.; O'Connor, Noah; Oakes, Graham H.; Passey, Stephen C.; Powling, Laurence C.
Organic Process Research and Development, 2001 , vol. 5, # 5 p. 479 - 490
