3-羟基-5,5-二甲基环己-2-烯-1-酮合成路线 （共 39 条）
反应条件
toluene-4-sulfonic acid in toluene
10 h; Heating;
参考文献
Amougay, Aicha; Pete, Jean-Pierre; Piva, Olivier
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 6 p. 625 - 635
反应条件
in ethanol
10 h; Heating;
参考文献
Skatetskii; Kozlov; Dikusar
Russian Journal of Organic Chemistry, 2007 , vol. 43, # 10 p. 1481 - 1487
反应条件
potassium hydroxide in 1,4-dioxane; water
T=0°C;
参考文献
Imashiro,F.; Maeda,S.; Takegoshi,K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 5213
反应条件
chloro-trimethyl-silane
T=20°C; 24 h;
参考文献
Zav'yalev, S. I.; Zavozin, A. G.; Kravchenko, N. E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 5.2 p. 1104 - 1106
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , vol. 40, # 5 p. 1227 - 1229
反应条件
1: trichlorophosphate / chloroform / 20 °C / Reflux
2: potassium iodide; zinc / methanol
View Scheme
参考文献
Chen, Li; Lin, Xianfeng; Qiu, Zongxing; Tang, Guozhi; Wang, Lisha; Wu, Jim Zhen; Yang, Wengang
Patent: US2011/195979 A1, 2011 ;
Title/Abstract Full Text Show Details
F. HOFFMANN-LA ROCHE AG; WANG, Lisha; CHEN, Li; QIU, Zongxing; TANG, Guozhi; LIN, Xianfeng; WU, Jim Zhen; YANG, Wengang
Patent: WO2011/94953 A1, 2011 ;
反应条件
in neat (no solvent)
T=20 - 120°C; 8 h; Microwave irradiationGreen chemistry;
参考文献
Edayadulla, Naushad; Lee, Yong Rok
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 10 p. 2963 - 2967
反应条件
1: 1) K2CO3, 2) conc. HCl / 1) CHCl3, RT, overnight, 2) ether, H2O
2: 2) 50percent aq. NaOH / 1) AcOH, reflux, 3 h, 2) EtOH, overnight
3: 72 percent / 0.5 h / 190 °C
View Scheme
参考文献
Nagarajan, Kuppuswamy; Talwalker, Purnachard K.; Goud, A. Nagana; Shah, Rashmi K.; Shenoy, Sharada J.; Desai, Narasimha D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 1113 - 1123
反应条件
4 A molecular sieve in dichloromethane
参考文献
Kurdyumov, Aleksey V.; Lin, Nan; Hsung, Richard P.; Gullickson, Glen C.; Cole, Kevin P.; Sydorenko, Nadiya; Swidorski, Jacob J.
Organic Letters, 2006 , vol. 8, # 2 p. 191 - 193
反应条件
acetic acid in isopropyl alcohol
0.666667 h; Heating;
参考文献
Kolos; Yurchenko; Orlov; Shishkina; Shishkin
Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 12 p. 1550 - 1559
