2-乙基氨基-N-(3-羟基-2,6-二甲基苯基)乙酰胺合成路线 (共 4 条)
反应条件
glucose-6-phosphate dehydrogenase; Tris-HCl buffer; glucose-6-phosphate; hepatic microsomal suspension; NADP in water T=37°C; Michaelis constant; Rate constant;
参考文献
Kawai; Fujita; Suzuki
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 11 p. 1219 - 1224
反应条件
glucose-6-phosphate dehydrogenase; Tris-HCl buffer; glucose-6-phosphate; hepatic microsomal suspension; NADP in water T=37°C; Michaelis constant; Rate constant;
参考文献
Suzuki; Fujita; Kawai
Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 1 p. 136 - 138
反应条件
T=37°C; in vitro methabolism; Vmax (maximal velocity of metabolism) and Km (Michaelis constant) for ring hydroxylation and N-deethylation in microsomal incubation mixture (pH 7.4);
参考文献
Kawai; Fujita; Suzuki
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 11 p. 1219 - 1224
反应条件
T=37°C; in vitro methabolism; Vmax (maximal velocity of metabolism) and Km (Michaelis constant) for ring hydroxylation and N-deethylation in microsomal incubation mixture (pH 7.4);
参考文献
Kawai; Fujita; Suzuki
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 11 p. 1219 - 1224