oxygen; carbon; copper(l) chloride T=400°C; Oxidation; chlorination; 2 h; Formation of xenobiotics;

oxygen; carbon; copper(l) chloride T=400°C; Oxidation; chlorination; 2 h; Formation of xenobiotics;

oxygen; carbon; copper(l) chloride T=400°C; Oxidation; chlorination; 2 h; Formation of xenobiotics;

oxygen; carbon; copper(l) chloride T=400°C; Oxidation; chlorination; 2 h; Formation of xenobiotics;

1: 89 g / LiAlH4 / tetrahydrofuran / 2.5 h / Heating 2: 77 g / 45percent HBr / H2O / 4 h / Heating 3: 18 g / Na2S*9H2O / 0.5 h 4: 13.4 g / 40percent CH3CO2OH / CHCl3 5: 5.9 g / 7 h / 230 °C 6: 5.4 g / NBS, AIBN / acetic anhydride / 1.5 h / Heating 7: 4.1 g / methanol / 2 h / Heating 8: 2.3 g / Et3N, diphenylphosphoryl azide / 6 h / Heating 9: 1.8 g / HCl / diethyl ether 10: 1.) NaNO2, HCl, 2.) CuCl, HCl / 1.) H2O, 0 deg C View Scheme

1: 77 g / 45percent HBr / H2O / 4 h / Heating 2: 18 g / Na2S*9H2O / 0.5 h 3: 13.4 g / 40percent CH3CO2OH / CHCl3 4: 5.9 g / 7 h / 230 °C 5: 5.4 g / NBS, AIBN / acetic anhydride / 1.5 h / Heating 6: 4.1 g / methanol / 2 h / Heating 7: 2.3 g / Et3N, diphenylphosphoryl azide / 6 h / Heating 8: 1.8 g / HCl / diethyl ether 9: 1.) NaNO2, HCl, 2.) CuCl, HCl / 1.) H2O, 0 deg C View Scheme

1: 13.4 g / 40percent CH3CO2OH / CHCl3 2: 5.9 g / 7 h / 230 °C 3: 5.4 g / NBS, AIBN / acetic anhydride / 1.5 h / Heating 4: 4.1 g / methanol / 2 h / Heating 5: 2.3 g / Et3N, diphenylphosphoryl azide / 6 h / Heating 6: 1.8 g / HCl / diethyl ether 7: 1.) NaNO2, HCl, 2.) CuCl, HCl / 1.) H2O, 0 deg C View Scheme

1: 18 g / Na2S*9H2O / 0.5 h 2: 13.4 g / 40percent CH3CO2OH / CHCl3 3: 5.9 g / 7 h / 230 °C 4: 5.4 g / NBS, AIBN / acetic anhydride / 1.5 h / Heating 5: 4.1 g / methanol / 2 h / Heating 6: 2.3 g / Et3N, diphenylphosphoryl azide / 6 h / Heating 7: 1.8 g / HCl / diethyl ether 8: 1.) NaNO2, HCl, 2.) CuCl, HCl / 1.) H2O, 0 deg C View Scheme

1: 5.9 g / 7 h / 230 °C 2: 5.4 g / NBS, AIBN / acetic anhydride / 1.5 h / Heating 3: 4.1 g / methanol / 2 h / Heating 4: 2.3 g / Et3N, diphenylphosphoryl azide / 6 h / Heating 5: 1.8 g / HCl / diethyl ether 6: 1.) NaNO2, HCl, 2.) CuCl, HCl / 1.) H2O, 0 deg C View Scheme

1: 4.1 g / methanol / 2 h / Heating 2: 2.3 g / Et3N, diphenylphosphoryl azide / 6 h / Heating 3: 1.8 g / HCl / diethyl ether 4: 1.) NaNO2, HCl, 2.) CuCl, HCl / 1.) H2O, 0 deg C View Scheme