1-(2-吡啶基)-哌嗪酮合成路线 (共 4 条)
反应条件
ammonium formate; palladium on activated charcoal in methanol 4 h; Heating / reflux;
参考文献
Castro Pineiro, Jose Luis; Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Shaw, Duncan Edward; Swain, Christopher John
Patent: US2003/236250 A1, 2003 ;
Location in patent: Page 39 ;
反应条件
hydrogenchloride in tetrahydrofuran; MeOH-NH3; diethyl ether
参考文献
Bryant, Helen Jane; Chambers, Mark Stuart; Jones, Philip; MacLeod, Angus Murray; Maxey, Robert James
Patent: US2003/125333 A1, 2003 ;
反应条件
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium tert-butylate; palladium diacetate / tetrahydrofuran 2: hydrogenchloride; methanol / diethyl ether View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 12 p. 3809 - 3812
反应条件
hydrogenchloride; methanol in diethyl ether
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 12 p. 3809 - 3812