3-甲基-2-苯并呋喃-1(3H)-酮合成路线 （共 49 条）
反应条件
1.1: hydrogenchloride; acetic acid / water / 0.08 h / Reflux 1.2: 2 h / 0 - 20 °C 2.1: sodium tetrahydroborate / methanol / 0.5 h / 0 - 20 °C / Inert atmosphere 3.1: hydrogenchloride; water / 48 h / 20 °C View Scheme
参考文献
Mangas-Sanchez, Juan; Busto, Eduardo; Gotor-Fernandez, Vicente; Gotor, Vicente
Organic Letters, 2012 , vol. 14, # 6 p. 1444 - 1447
反应条件
in tetrahydrofuran T=-70°C; 20 h;
参考文献
Knepper, Kerstin; Ziegert, Robert E.; Braese, Stefan
Tetrahedron, 2004 , vol. 60, # 39 p. 8591 - 8603
反应条件
1: 1.) NaH / 1.) THF, RT, 2.) 140 deg C, 2-5 * 10-5 Torr, 30 min 2: 40 percent / 350 °C / 0 Torr View Scheme
参考文献
Tomioka, Hideo; Kobayashi, Noriyuki; Murata, Shigeru; Ohtawa, Yasuki
Journal of the American Chemical Society, 1991 , vol. 113, # 23 p. 8771 - 8778
反应条件
1: 98 percent / pyridinium chlorochromate; celite / CH2Cl2 / 12 h / 20 °C 2: potassium fluoride / dimethylformamide / 48 h / 60 °C View Scheme
参考文献
Duan, Shaofeng; Cress, Karen; Waynant, Kris; Ramos-Miranda, Elias; Herndon, James W.
Tetrahedron, 2007 , vol. 63, # 14 p. 2959 - 2965
反应条件
1.1: BF3*OEt2 / CH2Cl2 2.1: LDA; HMPA 2.2: 92 percent / tetrahydrofuran 3.1: 32 percent / SmI2 / tetrahydrofuran / 20 °C View Scheme
参考文献
Yoda, Hidemi; Kohata, Naoki; Takabe, Kunihiko
Synthetic Communications, 2003 , vol. 33, # 7 p. 1087 - 1094
反应条件
1.1: LDA; HMPA 1.2: 92 percent / tetrahydrofuran 2.1: 32 percent / SmI2 / tetrahydrofuran / 20 °C View Scheme
参考文献
Yoda, Hidemi; Kohata, Naoki; Takabe, Kunihiko
Synthetic Communications, 2003 , vol. 33, # 7 p. 1087 - 1094
反应条件
1: CH2Cl2 / 2 h / 0 °C 2: SOCl2 3: 1.) n-BuLi, 2.) MgBr2*2Et2O, 4.) 4.5 M HCl View Scheme
参考文献
Boulet, Camille Andre; Poulton, Gerald Arthur
Heterocycles, 1989 , vol. 28, # 1 p. 405 - 410
反应条件
1: 1.) Mg / 1.) Et2O, reflux, 2.) Et2O, 1 h, 0 deg C 2: 75 percent / PCC/ Celite / CH2Cl2 / 12 h 3: 1.) LDA / 1.) THF, -78 deg C, 5 min 4: 1.) lithium 2,2,6,6-tetramethylpiperidine / 1.) THF, -78 deg C 5: 1.) HgO (red), I2 / 1.) benzene, 2.) 8 h, irradiation View Scheme
参考文献
Kobayashi, Kazuhiro; Konishi, Atsushi; Kanno, Yoshikazu; Suginome, Hiroshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 1 p. 111 - 116
反应条件
phosphoric acid microwave irradiation;
参考文献
Thirumamagal; Narayanasamy, Sureshbabu
Tetrahedron Letters, 2008 , vol. 49, # 3 p. 512 - 515
反应条件
1: SOCl2 2: 1.) n-BuLi, 2.) MgBr2*2Et2O, 4.) 4.5 M HCl View Scheme
参考文献
Boulet, Camille Andre; Poulton, Gerald Arthur
Heterocycles, 1989 , vol. 28, # 1 p. 405 - 410
