3-氧代-3-苯基丙酰胺合成路线 （共 38 条）
参考文献
Atkinson; Ingham; Thorpe
Journal of the Chemical Society, 1907 , vol. 91, p. 591
参考文献
Guareschi
Chem. Zentralbl., 1904 , vol. 75, # II p. 905
参考文献
Moureu; Lazennec
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1907 , vol. 144, p. 806
Bulletin de la Societe Chimique de France, 1907 , vol. <4> 1, p. 1070
反应条件
1: m-anisidine hydrochloride / toluene / 8 h / Heating 2: 34 percent / PPA / 0.33 h / 135 °C 3: 68 percent / POCl3 / 2 h / Heating View Scheme
参考文献
Giardina, Giuseppe A. M.; Sarau, Henry M.; Farina, Carlo; Medhurst, Andrew D.; Grugni, Mario; Raveglia, Luca F.; Schmidt, Dulcie B.; Rigolio, Roberto; Luttmann, Mark; Vecchietti, Vittorio; Hay, Douglas W. P.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 12 p. 1794 - 1807
反应条件
1: amalgamated aluminium; aqueous ethanol 2: sodium hypobromite View Scheme
参考文献
Abrams; Kipping
Journal of the Chemical Society, 1934 , p. 1988,1990
反应条件
tetraethylammonium bromide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in acetonitrile T=60°C; 1.83333 h;
参考文献
Bhalerao, Dinesh S.; Mahajan, Ulhas S.; Chaudhari, Kiran H.; Akamanchi, Krishnacharya G.
Journal of Organic Chemistry, 2007 , vol. 72, # 2 p. 662 - 665
反应条件
in water; acetonitrile
T=25°C; Equilibrium constant;
参考文献
Bunting, John W.; Kanter, James P.
Journal of the American Chemical Society, 1993 , vol. 115, # 25 p. 11705 - 11715
反应条件
1: o-anisidine hydrochloride / toluene / Heating
2: pyrophosphoric acid / 1 h / 135 °C
View Scheme
参考文献
Llinas-Brunet, Montse; Bailey, Murray D.; Ghiro, Elise; Gorys, Vida; Halmos, Ted; Poirier, Martin; Rancourt, Jean; Goudreau, Nathalie
Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6584 - 6594
反应条件
1: 2,3-dimethoxyaniline hydrochloride / toluene / Heating
2: pyrophosphoric acid / 1 h / 135 °C
View Scheme
参考文献
Llinas-Brunet, Montse; Bailey, Murray D.; Ghiro, Elise; Gorys, Vida; Halmos, Ted; Poirier, Martin; Rancourt, Jean; Goudreau, Nathalie
Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6584 - 6594
反应条件
1: m-isopropoxyaniline hydrochloride / toluene / Heating
2: pyrophosphoric acid / 1 h / 135 °C
View Scheme
参考文献
Llinas-Brunet, Montse; Bailey, Murray D.; Ghiro, Elise; Gorys, Vida; Halmos, Ted; Poirier, Martin; Rancourt, Jean; Goudreau, Nathalie
Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6584 - 6594
