1,4,8-三羟基-2-甲基蒽-9,10-二酮合成路线 （共 24 条）
反应条件
1: 76 percent / quinoline / 0.5 h / 160 °C 2: 85 percent / K2CO3 / acetone / 4 h / Heating 3: 78.5 percent / KOH, sulfamic acid / 9 h / Heating 4: 93 percent / conc. H2SO4, boric acid / 2 h / 130 - 140 °C View Scheme
参考文献
Gorelik, M. V.; Arinich, L. V.; Kotlyarevskii, O. I.; Fes'kova, E. A.
Journal of Organic Chemistry USSR (English Translation), 1986 , p. 129 - 138
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 1 p. 147 - 156
反应条件
1: 85 percent / K2CO3 / acetone / 4 h / Heating 2: 78.5 percent / KOH, sulfamic acid / 9 h / Heating 3: 93 percent / conc. H2SO4, boric acid / 2 h / 130 - 140 °C View Scheme
参考文献
Gorelik, M. V.; Arinich, L. V.; Kotlyarevskii, O. I.; Fes'kova, E. A.
Journal of Organic Chemistry USSR (English Translation), 1986 , p. 129 - 138
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 1 p. 147 - 156
反应条件
1: 73 percent / conc. H2SO4, boric acid / 0.5 h / 80 °C 2: 76 percent / quinoline / 0.5 h / 160 °C 3: 85 percent / K2CO3 / acetone / 4 h / Heating 4: 78.5 percent / KOH, sulfamic acid / 9 h / Heating 5: 93 percent / conc. H2SO4, boric acid / 2 h / 130 - 140 °C View Scheme
参考文献
Gorelik, M. V.; Arinich, L. V.; Kotlyarevskii, O. I.; Fes'kova, E. A.
Journal of Organic Chemistry USSR (English Translation), 1986 , p. 129 - 138
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 1 p. 147 - 156
反应条件
1: 77 percent / potassium acetate / dimethylsulfoxide / 1 h / 20 °C 2: 73 percent / conc. H2SO4, boric acid / 0.5 h / 80 °C 3: 76 percent / quinoline / 0.5 h / 160 °C 4: 85 percent / K2CO3 / acetone / 4 h / Heating 5: 78.5 percent / KOH, sulfamic acid / 9 h / Heating 6: 93 percent / conc. H2SO4, boric acid / 2 h / 130 - 140 °C View Scheme
参考文献
Gorelik, M. V.; Arinich, L. V.; Kotlyarevskii, O. I.; Fes'kova, E. A.
Journal of Organic Chemistry USSR (English Translation), 1986 , p. 129 - 138
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 1 p. 147 - 156
反应条件
1: 98 percent / Ag2O / CH2Cl2 / 2 h 2: 67 percent / NaHCO3 / CH2Cl2; diethyl ether; H2O / 5 h 3: 93 percent / CH2Cl2 / 1 h / Ambient temperature 4: KOH / 1) MeOH, H2O, heating, 15 min, 2) MeOH, H2O, air stream, 10 min 5: conc. HCl / CH2Cl2; diethyl ether / 0.17 h / 20 °C 6: 0.33 h / 150 °C 7: 1 N NaOH, Na2S2O4 / methanol / 0.17 h / Heating 8: conc. H2SO4, H2O / 10 h / 100 °C View Scheme
参考文献
Tolkiehn, Klaus; Krohn, Karsten
Chemische Berichte, 1980 , vol. 113, # 4 p. 1575 - 1583
反应条件
1: 93 percent / CH2Cl2 / 1 h / Ambient temperature 2: KOH / 1) MeOH, H2O, heating, 15 min, 2) MeOH, H2O, air stream, 10 min 3: conc. HCl / CH2Cl2; diethyl ether / 0.17 h / 20 °C 4: 0.33 h / 150 °C 5: 1 N NaOH, Na2S2O4 / methanol / 0.17 h / Heating 6: conc. H2SO4, H2O / 10 h / 100 °C View Scheme
参考文献
Tolkiehn, Klaus; Krohn, Karsten
Chemische Berichte, 1980 , vol. 113, # 4 p. 1575 - 1583
反应条件
1: 67 percent / NaHCO3 / CH2Cl2; diethyl ether; H2O / 5 h 2: 93 percent / CH2Cl2 / 1 h / Ambient temperature 3: KOH / 1) MeOH, H2O, heating, 15 min, 2) MeOH, H2O, air stream, 10 min 4: conc. HCl / CH2Cl2; diethyl ether / 0.17 h / 20 °C 5: 0.33 h / 150 °C 6: 1 N NaOH, Na2S2O4 / methanol / 0.17 h / Heating 7: conc. H2SO4, H2O / 10 h / 100 °C View Scheme
参考文献
Tolkiehn, Klaus; Krohn, Karsten
Chemische Berichte, 1980 , vol. 113, # 4 p. 1575 - 1583
反应条件
1: KOH / 1) MeOH, H2O, heating, 15 min, 2) MeOH, H2O, air stream, 10 min 2: conc. HCl / CH2Cl2; diethyl ether / 0.17 h / 20 °C 3: 0.33 h / 150 °C 4: 1 N NaOH, Na2S2O4 / methanol / 0.17 h / Heating 5: conc. H2SO4, H2O / 10 h / 100 °C View Scheme
参考文献
Tolkiehn, Klaus; Krohn, Karsten
Chemische Berichte, 1980 , vol. 113, # 4 p. 1575 - 1583
反应条件
1: 0.33 h / 150 °C 2: 1 N NaOH, Na2S2O4 / methanol / 0.17 h / Heating 3: conc. H2SO4, H2O / 10 h / 100 °C View Scheme
参考文献
Tolkiehn, Klaus; Krohn, Karsten
Chemische Berichte, 1980 , vol. 113, # 4 p. 1575 - 1583
反应条件
1: conc. HCl / CH2Cl2; diethyl ether / 0.17 h / 20 °C 2: 0.33 h / 150 °C 3: 1 N NaOH, Na2S2O4 / methanol / 0.17 h / Heating 4: conc. H2SO4, H2O / 10 h / 100 °C View Scheme
参考文献
Tolkiehn, Klaus; Krohn, Karsten
Chemische Berichte, 1980 , vol. 113, # 4 p. 1575 - 1583
