2,3,5,6-四氯-4-氟吡啶合成路线 (共 5 条)
反应条件
in gas Evaporation of ClFC5H3N and solvent CCl4 between 300 and 350 °C, chlorination at 580 °C (dwell time 18.5 s).;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
cesium fluoride in N,N-dimethyl-formamide T=80°C; 9 h; other reagents; Product distribution;
参考文献
Aksenov, V. V.; Vlasov, V. M.; Danilkin, V. I.; Naumova, O. Yu.; Rodionov, P. P.; et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, p. 1975
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 9 p. 2158 - 2159
反应条件
18-crown-6 ether; cesium fluoride in acetonitrile T=80°C; time required to the given yield of monofluoroaromatic compound with various mole ratios, with or without crown ether;
参考文献
Aksenov, V.V.; Vlasov, V.M.; Moryakina, I.M.; Rodionov, P.P.; Fadeeva, V.P.; et al.
Journal of Fluorine Chemistry, 1985 , vol. 28, p. 73 - 88
反应条件
in N,N-dimethyl-formamide At 115-120 °C.;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4, page 115 - 148
反应条件
Catalyst M-Chromium oxide T=520°C;
参考文献
Weigert, F. J.
Journal of Fluorine Chemistry, 1991 , vol. 53, # 1 p. 33 - 42