zinc in tetrahydrofuran; water under air atm., at room temp., cosolvent media: H2O(NH4Cl)/THF/Zn, alkyliodide was added dropwise to the alkyl tin halide in solvent mixt. over 15 min, reaction time 1.0 h; Zn was filtered off, aq. phase was extd. three times with n-pentane, organic phase was washed with sat. aq. NaCl and dried over MgSO4, solvent was removed, crude oil was distilled under vac.; (119Sn NMR monitoring);

R'MgBr

R'MgBr in diethyl ether refluxing, 3h;;

1: ethanol 2: Br2 3: R'MgBr / diethyl ether View Scheme

1: Br2 2: R'MgBr / diethyl ether View Scheme

1: H2O; KOH / water; ethanol View Scheme

1: KOH / ethanol View Scheme

1: KOH / ethanol View Scheme

1: H2O View Scheme

1: KOH View Scheme