2-氨基-4-三氟甲基噻唑-5-甲酸乙酯合成路线

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SCHERING CORPORATION; TING, Pauline, C.; ASLANIAN, Robert, G.; CAPLEN, Mary Ann; CAO, Jianhua; KIM, David, Won-Shik; KIM, Hyunjin; KUANG, Rongze; LEE, Joe, F.; SCHWERDT, John, H.; WU, Heping; ZHOU, Gang; ZORN, Nicolas
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363-58-62-氯-4,4,4-三氟乙酰乙酸乙酯

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

参考文献

Ting, Pauline C.; Aslanian, Robert; Caplen, Mary Ann; Cao, Jianhua; Chan, Tin-Yau; Kim, David; Kim, Hyunjin; Kim, Jae-Hun; Kuang, Rongze; Lee, Joe F.; Schwerdt, John; Wu, Heping; Zorn, Nicolas
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4544-43-82-溴-3-氧代-4,4,4-三氟丁酸乙酯+

17356-08-0

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

参考文献

Tanaka, Kiyoshi; Nomura, Kazuto; Oda, Hitoshi; Yoshida, Shouhei; Mitsuhashi, Keiryo
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 907 - 911

141860-78-8乙基3-氨基-4,4,4-三氟-2-丁烯酸酯+

65573-12-8

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

参考文献

Park, Young Seok; Kim, Kyongtae
Tetrahedron Letters, 1999 , vol. 40, # 35 p. 6439 - 6442

372-31-6三氟乙酰乙酸乙酯

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

参考文献

Journal of Heterocyclic Chemistry, , vol. 22, p. 1621 - 1630

141860-78-8乙基3-氨基-4,4,4-三氟-2-丁烯酸酯+

65573-12-8

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

参考文献

Tetrahedron Letters, , vol. 40, # 35 p. 6439 - 6442

17356-08-0+

372-31-6三氟乙酰乙酸乙酯

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

参考文献

Bioorganic and Medicinal Chemistry, , vol. 12, # 23 p. 6171 - 6182

4544-43-82-溴-3-氧代-4,4,4-三氟丁酸乙酯+

17356-08-0

344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯+

137929-14-7

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344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯

302963-97-92-[(叔丁氧基羰基)氨基]-4-(三氟甲基)-1,3-噻唑-5-羧酸

参考文献

Gillespie, Paul; Michoud, Christophe; Rupert, Kenneth Carey; Thakkar, Kshitij Chhabilbhai
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344-72-92-氨基-4-三氟甲基噻唑-5-甲酸乙酯+

110-46-3亚硝戊酯

72850-52-32-氯-4-三氟甲基-1,3-噻唑-5-羧酸乙酯

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ELI LILLY AND COMPANY; BASTIAN, Jolie, Anne; CLAY, Julia, Marie; COHEN, Jeffrey, Daniel; HIPSKIND, Philip, Arthur; LOBB, Karen, Lynn; SALL, Daniel, Jon; WILSON (NEE TAKAKUWA), Takako; THOMPSON, Michelle, Lee
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