4-氟-2-硝基-6-(三氟甲基)苯胺合成路线 （共 6 条）
参考文献
The State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University; The University of Oregon; The Regents of the University of California
Patent: US5514680 A1, 1996 ;
US 5514680 A
反应条件
1: concd. H2SO4, concd. HNO3 / 0 - 20 °C 2: concd. HCl / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4367 - 4379
反应条件
1: 12 h / 25 °C 2: concd. H2SO4, concd. HNO3 / 0 - 20 °C 3: concd. HCl / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4367 - 4379
反应条件
in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol
参考文献
The State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University; The University of Oregon; The Regents of the University of California
Patent: US5514680 A1, 1996 ;
US 5514680 A
反应条件
tin(ll) chloride in ethanol; ethyl acetate T=70°C; 0.583333 h;
参考文献
Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379
反应条件
in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol
参考文献
The State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University; The University of Oregon; The Regents of the University of California
Patent: US5514680 A1, 1996 ;
US 5514680 A
