反应条件
1: 86 percent / ethanol; H2O / 0.75 h / Heating 2: 91 percent / sulfuric acid / H2O / 4 h / Heating 3: 84 percent / LiAlH4 / diethyl ether / 1 h / Heating 4: 72 percent / 48percent HBr, H2SO4 / 3 h / Heating 5: 63 percent / NaOEt / 7 h / Heating 6: 98 percent / KOH / ethanol; H2O / 6 h / Heating 7: 95 percent / 170 °C 8: thionyl chloride / 0.75 h / Heating 9: 85 percent / AlCl3 / CS2 / 3 h / Heating View Scheme
参考文献
Ghoneim, Ola M.; Legere, Jacqueline A.; Golbraikh, Alexander; Tropsha, Alexander; Booth, Raymond G.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6640 - 6658