反应条件
1: 90 percent / 1 M aq.K2CO3 / tetrahydrofuran / Ambient temperature 2: kinetic resolution through transesterification using acylase I from Aspergillus sp. and vinyl butyrate 3: 1.) DMSO, (COCl)2, 2.) Et3N / 1.) CH2Cl2, -70 deg C, 90 min, 2.) CH2Cl2, from -70 deg C to RT 4: 76 percent / KMnO4, MgSO4 / acetone / 0.5 h / Ambient temperature 5: 94 percent / H2 / 10percent Pd/C / methanol / 6 h / 2327.2 Torr / Ambient temperature View Scheme
参考文献
Sanchez-Sancho, Francisco; Herradon, Bernardo
Tetrahedron Asymmetry, 1998 , vol. 9, # 11 p. 1951 - 1965
