反式-2-(2-硝基乙烯基)噻吩合成路线 （共 19 条）
反应条件
1: N-methylmorpholine / toluene / 16 h / Ambient temperature 2: 64 percent / H2, AcOH / 5percent Pd/C / 5 h / 70 °C / 2280 Torr 3: 69 percent / diphenyl phosphorazidate, N-methylmorpholine / dimethylformamide / 16 h / Ambient temperature 4: 31 percent / 4 N aq. HCl / dioxane / 4 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
hydroxide; dihydrogen peroxide; 1-(n-butyl)-3-methylimidazolium triflate T=25°C; 1 h;
参考文献
Bortolini, Olga; De Nino, Antonio; Fogagnolo, Marco; Fantin, Giancarlo; Mariuolo, Loredana; Tocci, Amedeo
Chemistry Letters, 2007 , vol. 36, # 3 p. 472 - 473
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; silica gel in benzene T=60°C; 20 h;
参考文献
Nakamura, Kaoru; Fujii, Masayuki; Oka, Shinzaburo; Ohno, Atsuyoshi
Chemistry Letters, 1985 , p. 523 - 526
参考文献
Syntex (U.S.A.) Inc.
Patent: US4906756 A1, 1990 ;
反应条件
bismuth(III) chloride; acetic acid; lithium chloride; palladium dichloride T=25°C; 20 h;
参考文献
Ohe, Toshiyuki; Uemura, Sakae
Bulletin of the Chemical Society of Japan, 2003 , vol. 76, # 7 p. 1423 - 1431
反应条件
acetic acid; lithium chloride; palladium dichloride T=25°C; 20 h;
参考文献
Ohe, Toshiyuki; Uemura, Sakae
Bulletin of the Chemical Society of Japan, 2003 , vol. 76, # 7 p. 1423 - 1431
反应条件
acetic acid; lithium chloride; palladium dichloride T=25°C; 20 h;
参考文献
Ohe, Toshiyuki; Uemura, Sakae
Bulletin of the Chemical Society of Japan, 2003 , vol. 76, # 7 p. 1423 - 1431
反应条件
acetic acid; lithium chloride; palladium dichloride T=25°C; 20 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 76, # 7 p. 1423 - 1431
反应条件
copper(II) bis(trifluoromethanesulfonate); triethylamine in acetonitrile
5 h; Reflux;
参考文献
Su, Weike; Ding, Kai; Chen, Zhiwei
Tetrahedron Letters, 2009 , vol. 50, # 6 p. 636 - 639
