2-氨基-3,5-二溴-4-甲基吡啶合成路线 （共 4 条）
反应条件
bromine in sulfuric acid
参考文献
SmithKline Beecham Corporation
Patent: US6440993 B1, 2002 ;
US 6440993 B1
反应条件
bromine in acetic acid T=20°C; 1 h;
参考文献
Heterocycles, , vol. 38, # 3 p. 529 - 540
反应条件
hydrogen bromide; dihydrogen peroxide T=70°C; 1 h; Product distribution;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 331, # 3 p. 369 - 374
反应条件
1: With n-butyllithium in tetrahydrofuran; pentane T=-78°C; 1 h; 2: With sodium hydroxide; water in tetrahydrofuran; pentane pH=~ 12;
参考文献
AnorMED Inc.
Patent: US2005/277668 A1, 2005 ;
Location in patent: Page/Page column 28 ;
US 20050277668 A1
