(S)-3-氨基哌啶-2-酮盐酸盐合成路线 （共 16 条）
反应条件
sodium methylate in methanol 2 h; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 23 p. 4264 - 4269
反应条件
potassium hydroxide in water T=0 - 20°C; 18 h;
参考文献
CAMBRIDGE ENTERPRISE LIMITED
Patent: WO2009/16390 A1, 2009 ;
Location in patent: Page/Page column 13-14 ;
反应条件
potassium phosphate buffer; pyridoxal 5'-phosphate in water T=37°C; α-amino-ε-caprolactam racemase from Achromobacter obae, pH 8; other pH values; Michaelis constant and Vmax determination;
参考文献
Ahmed, Syed Ashrafuddin; Esaki, Nobuyoshi; Tanaka, Hidehiko; Soda, Kenji
Agricultural and Biological Chemistry, 1983 , vol. 47, # 5 p. 1149 - 1150
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=5 - 20°C;
参考文献
Chugai Seiyaku Kabushiki Kaisha
Patent: US5051509 A1, 1991 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=5 - 20°C;
参考文献
Chugai Seiyaku Kabushiki Kaisha
Patent: US5051509 A1, 1991 ;
反应条件
potassium phosphate buffer; pyridoxal 5'-phosphate in water T=37°C; α-amino-ε-caprolactam racemase from Achromobacter obae, pH 8; other pH values; Michaelis constant and Vmax determination;
参考文献
Ahmed, Syed Ashrafuddin; Esaki, Nobuyoshi; Tanaka, Hidehiko; Soda, Kenji
Agricultural and Biological Chemistry, 1983 , vol. 47, # 5 p. 1149 - 1150
