N-甲基-4-(3,4-二甲氧基苯基)-4-氰基-5-己基甲胺合成路线 （共 21 条）
反应条件
potassium iodide in ethanol; water 72 h;
参考文献
Wang, Cheng; Wang, Tao; Zhou, Nan; Pan, Xiao-Yan; He, Huai-Zhen
Journal of Asian Natural Products Research, 2014 , vol. 16, # 3 p. 304 - 311
反应条件
sodium hydroxide in methanol; water 22 h; Heating;
参考文献
Laguerre, M.; Boyer, C.; Carpy, A.; Panconi, E.; Cognic, F.; Vaugien, B.
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 4 p. 351 - 359
反应条件
1: 1.) NaH / 1.) DMF, RT, 5 h, 2.) RT, overnight 2: 1.) NaH / 1.) DMF, 80 deg C, 5 h, 2.) 80 deg C, 20 h 3: 100 percent / NaOH / methanol; H2O / 22 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 25, # 4 p. 351 - 359
反应条件
1: 1.) NaH / 1.) DMF, 80 deg C, 5 h, 2.) 80 deg C, 20 h 2: 100 percent / NaOH / methanol; H2O / 22 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 25, # 4 p. 351 - 359
反应条件
NADPH in water; dimethyl sulfoxide T=37°C; 1 h; Microbiological reaction;
参考文献
Rapid Communications in Mass Spectrometry, , vol. 24, # 7 p. 939 - 957
反应条件
cytochrome P450 BM3 chimera variant 11113311 T=37°C; 1 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Chemistry - A European Journal, , vol. 15, # 43 p. 11723 - 11729
反应条件
cytochrome P450 BM3 chimera variant 21313111 T=37°C; 1 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Sawayama, Andrew M.; Chen, Michael M. Y.; Kulanthaivel, Palaniappan; Kuo, Ming-Shang; Hemmerle, Horst; Arnold, Frances H.
Chemistry - A European Journal, 2009 , vol. 15, # 43 p. 11723 - 11729
反应条件
cytochrome P450 BM3 chimera variant 23132233-R1 T=37°C; 1 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Chemistry - A European Journal, , vol. 15, # 43 p. 11723 - 11729
反应条件
cytochrome P450 BM3 variant F87L T=37°C; 1 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Chemistry - A European Journal, , vol. 15, # 43 p. 11723 - 11729
反应条件
cytochrome P450 BM3 chimera variant 22313231 T=37°C; 1 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Chemistry - A European Journal, , vol. 15, # 43 p. 11723 - 11729
