palladium diacetate in methanol T=25°C; 8 h;

palladium diacetate in methanol T=25°C; 8 h;

copper; magnesium sulfate

potassium acetate in water; acetone T=20°C;

1: palladium diacetate / tetrahydrofuran / 12 h / 40 °C 2: hydrogen; palladium diacetate / tetrahydrofuran / 5 h / 25 °C 3: sodium ethanolate / tetrahydrofuran / 15 h / 36 °C 4: tetrahydrofuran / 24 h / 36 °C View Scheme

copper trifluoromethanesulfonate in acetonitrile T=0 - 20°C; 26 h;

copper trifluoromethanesulfonate in acetonitrile T=20°C; 23 h;

1: palladium diacetate / tetrahydrofuran / 12 h / 40 °C 2: hydrogen; palladium diacetate / tetrahydrofuran / 5 h / 25 °C 3: sodium ethanolate / tetrahydrofuran / 15 h / 36 °C View Scheme

&nbsp;(i) aq. HCl, NaNO₂, (ii) NaBF₄;&nbsp;&nbsp;Multistep reaction;&nbsp;<br /> &nbsp;

Stage #1: &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=-15&deg;C;&nbsp;0.5&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '969510', constants.ctx, '0')">isopentyl nitrite</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=-15 - 0&deg;C;&nbsp;2&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br /> &nbsp;