BOC-甘氨酸-N-羟基琥柏酰亚胺酯合成路线 （共 21 条）
反应条件
dicyclohexyl-carbodiimide in ethylene glycol dimethyl ether T=0°C;
参考文献
Detsi, Anastasia; Micha-Screttas, Maria; Igglessi-Markopoulou, Olga
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 15 p. 2443 - 2449
反应条件
1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide in acetonitrile T=0°C; 2 h;
参考文献
WO2006/17352 A1, ;
Page/Page column 38 ;
参考文献
SORIN BIOMEDICA S.p.A.
Patent: EP659764 A2, 1995 ;
反应条件
triethylamine in N,N-dimethyl-formamide T=20°C; 0.5 h;
参考文献
Bailen, Miguel A; Chinchilla, Rafael; Dodsworth, David J; Najera, Carmen
Tetrahedron Letters, 2002 , vol. 43, # 9 p. 1661 - 1664
反应条件
pyridine T=22°C; 1 h;
参考文献
Il'ina, A. V.; Davidovich, Yu. A.; Rogozhin, S. V.
J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 8 p. 1904 - 1907,1696 - 1698
反应条件
4-methyl-morpholine in tetrahydrofuran; acetonitrile Ambient temperature;
参考文献
Jaoudai, Mahmoud; Martinez, Jean; Castro, Bertrand
Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2364 - 2367
反应条件
4-methyl-morpholine in acetonitrile
参考文献
Jaouadi, M.; Selve, C.; Dormoy, J. R.; Castro, B.; Martinez, J.
Tetrahedron Letters, 1985 , vol. 26, # 14 p. 1721 - 1722
反应条件
in chloroform; ethyl acetate
反应条件
1: sodium hydroxide / water; 1,4-dioxane / 0 - 20 °C 2: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C View Scheme
参考文献
ACS Medicinal Chemistry Letters, , vol. 4, # 4 p. 402 - 407
反应条件
1: 87 percent / H2O; dioxane / 4 h / 20 °C 2: 68 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 20 °C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 87, # 5 p. 1077 - 1089
