3-(苄氧基)-n-甲基苯胺合成路线 （共 7 条）
反应条件
1: in tetrahydrofuran T=5 - 20°C; 24 h; 2: With water; ammonium chloride in tetrahydrofuran
参考文献
Butler, Christopher R.; Edwards, James P.; Fourie, Anne M.; Grice, Cheryl A.; Karlsson, Lars; Savall, Brad M.; Tays, Kevin L.; Wei, Jianmei
Patent: US2006/223792 A1, 2006 ;
Location in patent: Page/Page column 24 ;
US 20060223792 A1
反应条件
1: With sodium methylate in methanol T=20°C; 12 h; 2: With sodium tetrahydroborate in methanol T=20 - 80°C; 3 h; 3: With potassium hydroxide in methanol; water
参考文献
Otomo, Akira; Aoki, Isao; Miki, Hideki; Tazawa, Hidehisa; Yokoyama, Shiyoshi
Patent: US2012/172599 A1, 2012 ;
Location in patent: Page/Page column 115 ;
反应条件
potassium hydroxide in methanol 12 h; Heating;
参考文献
Griera; Armengol; Reyes; Alvarez; Palomer; Cabre; Pascual; Garcia; Mauleon
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 7-8 p. 547 - 570
反应条件
sodium; xylene anschliessenden Behandeln mit Methylsulfat und Erwaermen des Reaktionsprodukts mit wss.-aethanol.Kalilauge;
参考文献
Griera; Armengol; Reyes; Alvarez; Palomer; Cabre; Pascual; Garcia; Mauleon
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 7-8 p. 547 - 570
反应条件
1: 74 percent / K2CO3 / acetone / 8 h / Heating 2: 98 percent / lithium diisopropylamide / tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) room temperature, 2 h 3: 91 percent / KOH / methanol / 12 h / Heating View Scheme
参考文献
Morton; Slaunwhite
Journal of Biological Chemistry, 1949 , vol. 179, p. 259,264
反应条件
1: 74 percent / K2CO3 / acetone / 8 h / Heating 2: 98 percent / lithium diisopropylamide / tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) room temperature, 2 h 3: 91 percent / KOH / methanol / 12 h / Heating View Scheme
参考文献
Morton; Slaunwhite
Journal of Biological Chemistry, 1949 , vol. 179, p. 259,264
反应条件
1: sodium methylate / methanol / 24 h / 20 °C 2: sodium tetrahydroborate / methanol / 2 h / Reflux View Scheme
参考文献
Piao, Xianqing; Zhang, Xianmin; Mori, Yuichi; Koishi, Masayuki; Nakaya, Akinari; Inoue, Shinichiro; Aoki, Isao; Otomo, Akira; Yokoyama, Shiyoshi
Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 1 p. 47 - 54
