4-(三氟甲基)亚苯基肼合成路线 （共 13 条）
反应条件
hydrazine hydrate Ambient temperature;
参考文献
Tavares; Penna; Amaral
Bollettino Chimico Farmaceutico, 1997 , vol. 136, # 3 p. 244 - 249
反应条件
1: With 4-methyl-morpholine; isobutyl chloroformate in tetrahydrofuran T=20°C; 1.5 h; 2: With hydrazine in tetrahydrofuran 5 h;
参考文献
Romine, Jeffrey L.; Martin, Scott W.; Meanwell, Nicholas A.; Gribkoff, Valentin K.; Boissard, Christopher G.; Dworetzky, Steven I.; Natale, Joanne; Moon, Sandra; Ortiz, Astrid; Yeleswaram, Swamy; Pajor, Lorraine; Gao, Qi; Starrett Jr., John E.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 3 p. 528 - 542
反应条件
pyridine; hydrazine in tetrahydrofuran T=70°C; 17 h;
参考文献
EP1607392 A1, ;
Page/Page column 22 ;
参考文献
Ukrainskii Khimicheskii Zhurnal (Russian Edition), , vol. 23, p. 634
Chem.Abstr., , p. 9979
反应条件
water in dimethyl sulfoxide T=37°C; pH=7.4; aq. phosphate buffer;
参考文献
Dalton Transactions, , vol. 41, # 30 p. 9192 - 9201
反应条件
1: neat (no solvent) / 120 °C 2: palladium diacetate; copper diacetate; [2,2']bipyridinyl; potassium phosphate / dimethyl sulfoxide / 12 h / 100 °C View Scheme
参考文献
Salvanna; Reddy, Gandolla Chinna; Das, Biswanath
Tetrahedron, 2013 , vol. 69, # 9 p. 2220 - 2225
反应条件
hydrogenchloride in ethanol Heating;
参考文献
Li, Ming; Wen, Lirong; Wang, Xiao; Yao, Changsheng; Fu, Weijun; Zhao, Guilong; Hu, Fangzhong; Yang, Huazheng
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 2 p. 483 - 488
反应条件
hydrogenchloride in 1,4-dioxane; ethanol T=150°C; 0.166667 h; Microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 50, # 2 p. 212 - 215
反应条件
tin; phosphoric acid; boric acid; oxalic acid; carbon; acetic acid in ethanol; water T=70°C; Electrolysis;
参考文献
Mentel, Matthias; Beier, Matthias J.; Breinbauer, Rolf
Synthesis, 2009 , # 9 art. no. T18908SS, p. 1463 - 1468
参考文献
Wertz, Sebastian; Kodama, Shintaro; Studer, Armido
Angewandte Chemie - International Edition, 2011 , vol. 50, # 48 p. 11511 - 11515
