(2R,3R,4S,5S)-2-(6-氨基嘌呤-9-基)-5-(甲基亚磺酰甲基)四氢呋喃-3,4-二醇合成路线 （共 2 条）
反应条件
1: 74 percent / 4-(dimethylamino)pyridine, Et3N / acetonitrile / 1 h 2: 1) (dimethylamino)sulfur trifluoride, 2) NH3 / 1) CHCl3, 55 deg C, 2.5-3 h, 2) MeOH, r.t., 2.5 h View Scheme
参考文献
Sufrin, Janice R.; Spiess, Arthur J.; Kramer, Debora L.; Libby, Paul R.; Porter, Carl W.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 997 - 1001
反应条件
1: 74 percent / 4-(dimethylamino)pyridine, Et3N / acetonitrile / 1 h 2: 1) (dimethylamino)sulfur trifluoride, 2) NH3 / 1) CHCl3, 55 deg C, 2.5-3 h, 2) MeOH, r.t., 2.5 h View Scheme
参考文献
Sufrin, Janice R.; Spiess, Arthur J.; Kramer, Debora L.; Libby, Paul R.; Porter, Carl W.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 997 - 1001
