1-(2-氯乙氧基)-4-甲氧基苯合成路线 (共 4 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C; Alkylation;
参考文献
Plotkin, Michael; Chen, Sanyou; Spoors, P. Grant
Tetrahedron Letters, 2000 , vol. 41, # 14 p. 2269 - 2273
反应条件
sodium hydroxide in methanol 22 h; Heating;
参考文献
Corsano, S; Strappaghetti, G; Codagnone, A; Scapicchi, R; Marucci, G
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 545 - 549
反应条件
potassium hydroxide; water
参考文献
Harris; Stewart
Canadian Journal of Research, Section B: Chemical Sciences, 1949 , vol. 27, p. 740
反应条件
1: 81 percent / Fe(0); bromine / CH2Cl2
2: n-BuLi / tetrahydrofuran / -40 °C
3: -40 °C
View Scheme
参考文献
Plotkin, Michael; Chen, Sanyou; Spoors, P. Grant
Tetrahedron Letters, 2000 , vol. 41, # 14 p. 2269 - 2273