2-氯乙基 4-硝基苯基醚合成路线 (共 24 条)
参考文献
PROTEOSYS AG
Patent: WO2004/35534 A2, 2004 ;
Location in patent: Page/Page column 10 ;
反应条件
1: 1.) NaH / 1.) DMF, 100 deg C, 10 min, 2.) DMF, heating, 5.5 h
2: 69 percent / Fe, 5N aq. HCl / 0.33 h / Heating
View Scheme
参考文献
Cross, Peter E.; Dickinson, Roger P.; Parry, M. John; Randall, Michael J.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1427 - 1432
反应条件
potassium tert-butylate in tert-butyl alcohol
参考文献
Oae,S.; Yano,Y.
Tetrahedron, 1968 , vol. 24, p. 5721 - 5729
反应条件
in water; isopropyl alcohol
T=100°C; 4 h;
参考文献
Maynard, George; Xie, LingHong; Rachwal, Stanislaw
Patent: US2002/128236 A1, 2002 ;