2-(3-溴丙氧基)四氢-2H-吡喃合成路线 （共 28 条）
反应条件
n-butyllithium; lithium iodide in tetrahydrofuran; hexane
from 0 degC to room temp.;
参考文献
Alcaraz; Harnett; Mioskowski; Martel; Le Gall; Shin, Dong-Soo; Falck
Tetrahedron Letters, 1994 , vol. 35, # 30 p. 5453 - 5456
反应条件
(i) , (ii) PPh3, Br2; Multistep reaction;
参考文献
Roumestant,M.L. et al.
Journal of the Chemical Society, Chemical Communications, 1976 , p. 479 - 480
反应条件
1: lithium, ammonia, ferric nitrate decahydrate
2: 84 percent / nickel(II)acetate tetrahydrate, sodium borohydride / ethanol / 4.5 h
View Scheme
参考文献
Ireland, Robert E.; Brown, Frank R.
Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1868 - 1880
反应条件
ammonia; sodium
Alkylation;
参考文献
Mo, W.-P.; Burger, B. V.; LeRoux, M.; Spies, H. S. C.
Journal of Chemical Ecology, 1995 , vol. 21, # 8 p. 1191 - 1216
反应条件
in dimethyl sulfoxide
T=10 - 20°C;
参考文献
Ettmayer, Peter; Billich, Andreas; Baumruker, Thomas; Mechtcheriakova, Diana; Schmid, Heide; Nussbaumer, Peter
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1555 - 1558
反应条件
1: tetrahydrofuran; hexamethylphosphoric acid triamide / 3 h / 0 - 25 °C
2: KF / dimethylformamide / 0.5 h / 55 °C
View Scheme
参考文献
Stefani, Helio A.; Cardoso, Lincoln D. G.; Valduga, Claudete J.; Zeni, Gilson
Phosphorus, Sulfur and Silicon and Related Elements, 2001 , vol. 171-172, p. 167 - 172
反应条件
Yield given. Multistep reaction;
参考文献
Carling, Robert W.; Clark, J. Stephen; Holmes, Andrew B.; Sartor, Dirk
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 1 p. 95 - 102
反应条件
sodium iodide in acetone
T=25°C; 5 h;
参考文献
Gupta, Atul; Beazley, Gloria; Lee, Jean; Berube, Gervais
Synthetic Communications, 2007 , vol. 37, # 12 p. 2031 - 2037
