2-(3-溴丙氧基)四氢-2H-吡喃合成路线 （共 28 条）
反应条件
pyridinium p-toluenesulfonate in dichloromethane 5 h;
参考文献
Gupta, Atul; Beazley, Gloria; Lee, Jean; Berube, Gervais
Synthetic Communications, 2007 , vol. 37, # 12 p. 2031 - 2037
反应条件
2: CBr3, PPh3 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 11 p. 1365 - 1370
反应条件
N-bromosuccinmide; boron trifluoride diethyl etherate in acetonitrile T=20°C; 2 h;
参考文献
Kumar, Brijesh; Aga, Mushtaq A.; Mukherjee, Debaraj; Chimni, Swapandeep S.; Taneja, Subhash C.
Tetrahedron Letters, 2009 , vol. 50, # 46 p. 6236 - 6240
反应条件
carbon tetrabromide; triphenylphosphine
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 11 p. 1365 - 1370
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in toluene T=67°C; 1 h;
参考文献
Brown, Thomas J.; Chapman, Robert F.; Cook, David C.; Hart, Terance W.; McLay, Iain M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 20 p. 3613 - 3624
反应条件
1.)11 h, 2.)HMPA, ether; Yield given. Multistep reaction;
参考文献
Apparu, Marcel; Crandall, Jack K.
Journal of Organic Chemistry, 1984 , vol. 49, # 12 p. 2125 - 2130
反应条件
sodium; toluene-4-sulfonic acid Yield given. Multistep reaction;
参考文献
Lin, Chu-Chung; Hsia, Ket-Shang; Wu, Hsien-Jen
Journal of the Chinese Chemical Society (Taipei, Taiwan), 1993 , vol. 40, # 6 p. 587 - 592
反应条件
silica-supported NaHSO4 in methanol T=20°C; 0.25 h;
参考文献
Kumar, K. Ravi; Satyanarayana; Reddy, B. Srinivasa
Chinese Journal of Chemistry, 2012 , vol. 30, # 5 p. 1189 - 1191
反应条件
1: sodium iodide / acetone / 12 h / 60 °C / |Sealed tube 2: bis(acetylacetonate)nickel(II); N,N,N',N,-tetramethylethylenediamine / tetrahydrofuran / 0.17 h / 0 - 25 °C / |Inert atmosphere View Scheme
参考文献
Guisan-Ceinos, Manuel; Soler-Yanes, Rita; Collado-Sanz, Daniel; Phapale, Vilas B.; Bunuel, Elena; Cardenas, Diego J.
Chemistry - A European Journal, 2013 , vol. 19, # 26 p. 8405 - 8410
反应条件
1: BuLi / tetrahydrofuran / 2 h / Ambient temperature 2: 0.507 g / aq. HCl / tetrahydrofuran View Scheme
参考文献
Reddy, G. Bhasker; Mitra, R.B.
Synthetic Communications, 1986 , vol. 16, # 13 p. 1723 - 1730
