3-(4-苄氧基苯基)-异噁唑-5-甲醛合成路线 （共 3 条）
反应条件
silica gel; pyridinium chlorochromate in dichloromethane 5 h;
参考文献
SK HOLDINGS CO., LTD.; PARK, Cheol-Hyoung; MIN, Hye-Kyung; LIM, Mi-Jung; LEE, Ji-Won; CHUNG, Jin-Yong; RYU, Choon-Ho; YOON, Yeo-Jin; JI, Mi-Kyung; PARK, Joo-Young
Patent: WO2010/98600 A2, 2010 ;
Location in patent: Paragraph 782-783 ;
反应条件
1.1: NH2OH*HCl; Na2CO3 / ethanol; H2O / 1 h / 60 °C 2.1: N-chlorosuccinimide; pyridine / tetrahydrofuran / 0.5 h / 60 °C 2.2: triethylamine / tetrahydrofuran / 2 h / 50 °C 3.1: pyridinium chlorochromate; silica gel / CH2Cl2 / 5 h View Scheme
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
反应条件
1.1: N-chlorosuccinimide; pyridine / tetrahydrofuran / 0.5 h / 60 °C 1.2: triethylamine / tetrahydrofuran / 2 h / 50 °C 2.1: pyridinium chlorochromate; silica gel / CH2Cl2 / 5 h View Scheme
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
