N-甲基-[1,1-联苯]-4-胺合成路线 （共 28 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 0.5 h;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED
Patent: US2009/239848 A1, 2009 ;
Location in patent: Page/Page column 36 ;
US 20090239848 A1
反应条件
sodium hydroxide in water Hydrolysis; 40 h; Heating;
参考文献
Srivastava, Sanjay; Ruane, Patrick H.; Toscano, John P.; Sullivan, Michael B.; Cramer, Christopher J.; Chiapperino, Dominic; Reed, Elizabeth C.; Falvey, Daniel E.
Journal of the American Chemical Society, 2000 , vol. 122, # 34 p. 8271 - 8278
反应条件
triethylsilane; tin(IV) chloride in dichloromethane T=20 - 25°C; Rearrangement; Reduction;
参考文献
Lopez, Francisco J.; Nitzan, Dov
Tetrahedron Letters, 1999 , vol. 40, # 11 p. 2071 - 2074
反应条件
N,N'-dimethyl-N,N'-propyleneurea; sodium hydride in N,N-dimethyl-formamide T=100°C;
参考文献
Coutts, Ian G. C.; Southcott, Mark R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 767 - 771
反应条件
4,4'-(phenylphosphinediyl)bis(2,6-dimethylmorpholine); caesium carbonate; tris(dibenzylideneacetone)dipalladium (0) in 1,4-dioxane Suzuki-Miyaura coupling; 26 h; Heating;
参考文献
Cho, Su-Dong; Kim, Ho-Kyun; Yim, Heung-seop; Kim, Mi-Ra; Lee, Jin-Kook; Kim, Jeum-Jong; Yoon, Yong-Jin
Tetrahedron, 2007 , vol. 63, # 6 p. 1345 - 1352
反应条件
1: 73 percent / H2SO4 / 4 h / 70 °C 2: 91 percent / KOH / dimethylsulfoxide / 0.67 h / 20 °C 3: 96 percent / NaOH / H2O / 40 h / Heating View Scheme
参考文献
Schmitt, Martin L.; Hauser, Alexander-Thomas; Carlino, Luca; Pippel, Martin; Schulz-Fincke, Johannes; Metzger, Eric; Willmann, Dominica; Yiu, Teresa; Barton, Michelle; Schuele, Roland; Sippl, Wolfgang; Jung, Manfred
Journal of Medicinal Chemistry, 2013 , vol. 56, # 18 p. 7334 - 7342
反应条件
perchloric acid in acetonitrile T=22°C; KineticsProduct distribution;
参考文献
Chiapperino, Dominic; McIlroy, Sean; Falvey, Daniel E.
Journal of the American Chemical Society, 2002 , vol. 124, # 14 p. 3567 - 3577
反应条件
1: 91 percent / KOH / dimethylsulfoxide / 0.67 h / 20 °C 2: 96 percent / NaOH / H2O / 40 h / Heating View Scheme
参考文献
Srivastava, Sanjay; Ruane, Patrick H.; Toscano, John P.; Sullivan, Michael B.; Cramer, Christopher J.; Chiapperino, Dominic; Reed, Elizabeth C.; Falvey, Daniel E.
Journal of the American Chemical Society, 2000 , vol. 122, # 34 p. 8271 - 8278
反应条件
aluminium trichloride T=20°C; 1 h;
参考文献
Ohwada; Nara; Sakamoto; Kikugawa
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 22 p. 3064 - 3068
反应条件
perchloric acid in acetonitrile T=22°C; KineticsProduct distribution;
参考文献
Chiapperino, Dominic; McIlroy, Sean; Falvey, Daniel E.
Journal of the American Chemical Society, 2002 , vol. 124, # 14 p. 3567 - 3577
