2-羟基-2-(4-甲氧基苯基)乙腈合成路线 （共 38 条）
反应条件
1: chromium (VI)-oxide; acetic acid 2: palladium; acetic acid / Hydrogenation View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1931 , vol. 269, p. 581,600
Justus Liebigs Annalen der Chemie, 1935 , vol. 519, p. 291,295
反应条件
1: H2 / Raney nickel 2: NaHSO3 3: H(+) 4: KOH / ethanol View Scheme
参考文献
Matthews, Barry R.; Gountzos, Helen; Jackson, W. Roy; Watson, Keith G.
Tetrahedron Letters, 1989 , vol. 30, # 38 p. 5157 - 5158
反应条件
2-ethyl-1-hexanoic acid in toluene T=200°C; 0.333333 h; Microwave irradiationSealed tube; Overall yield = 67 percent; regioselective reaction;
参考文献
Ma, Longle; Chen, Weijie; Seidel, Daniel
Journal of the American Chemical Society, 2012 , vol. 134, # 37 p. 15305 - 15308
反应条件
sodium t-butanolate in 1,4-dioxane T=105°C; 2 h; Yield given. Yields of byproduct given;
参考文献
Kossmehl, Gerhard; Nuck, Rolf
Chemische Berichte, 1981 , vol. 114, # 8 p. 2914 - 2920
反应条件
1: HCl; diethyl ether 2: diethyl ether View Scheme
参考文献
Kaji; Nagashima
Yakugaku Zasshi, 1956 , vol. 76, p. 1250,1253
Chem.Abstr., 1957 , p. 4309
参考文献
Kaji; Nagashima
Yakugaku Zasshi, 1956 , vol. 76, p. 1250,1253
Chem.Abstr., 1957 , p. 4309
参考文献
Kaji; Nagashima
Yakugaku Zasshi, 1956 , vol. 76, p. 1247,1250, 1371, 1372
Chem.Abstr., 1957 , p. 4308
参考文献
Kaji; Nagashima
Yakugaku Zasshi, 1956 , vol. 76, p. 1247,1250, 1371, 1372
Chem.Abstr., 1957 , p. 4308
反应条件
lipase PS-30 in diethyl ether T=15°C; 29 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Xu, Qing; Xie, Yongli; Geng, Xiaohong; Chen, Peiran
Tetrahedron, 2010 , vol. 66, # 3 p. 624 - 630
反应条件
(3R,4S)-4-(3,5-dinitrobenzamido)-1,2,3,4-tetrahydrophenanthren-3-yl covalently linked to 3-propyl silica surface in hexane; acetic acid; isopropyl alcohol T=25°C; pH=3.6; Resolution of racemate;
参考文献
Aneja, Ritu; Luthra, Pratibha Mehta; Ahuja, Satinder
Chirality, 2010 , vol. 22, # 5 p. 479 - 485
