N-甲酰基-L-天冬氨酰-L-苯丙氨酸甲酯合成路线 （共 8 条）
反应条件
sodium acetate; acetic acid in ethyl acetate
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US5302743 A1, 1994 ;
反应条件
hydrogen; Rh-(R)-prophos in tetrahydrofuran T=23°C; P=760 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fuganti, Claudio; Grasselli, Piero; Malpezzi, Luciana
Journal of Organic Chemistry, 1986 , vol. 51, # 7 p. 1126 - 1128
反应条件
sodium acetate; acetic anhydride in water; acetic acid
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US5302743 A1, 1994 ;
反应条件
acetic acid in butanone
参考文献
Ajinomoto Co., Inc.
Patent: US4071511 A1, 1978 ;
反应条件
hydrogenchloride 1.) neutral proteinase (Bacillus megaterium), 20 deg C, 3 days, 2.) ethanol, water, 2 h; Yield given. Multistep reaction;
参考文献
Kotlova, E. K.; Levin, E. D.; Yusupova, M. P.; Rozynov, B. V.; Stepanov, V. M.
Russian Journal of Bioorganic Chemistry, 1994 , vol. 20, # 11 p. 678 - 686
Bioorganicheskaya Khimiya, 1994 , vol. 20, # 11 p. 1186 - 1195
反应条件
in water T=0 - 3°C; variation of concentration, pH and solvent; Product distribution;
参考文献
Kuhl, Peter; Schaaf, Regina
Zeitschrift fuer Chemie (Stuttgart, Germany), 1990 , vol. 30, # 6 p. 212 - 213
反应条件
hydroxylamine hydrochloride in methanol
参考文献
Ajinomoto Co., Inc.
Patent: US4021418 A1, 1977 ;
反应条件
in water; tert-butyl alcohol
参考文献
Ajinomoto Co., Inc.
Patent: US4071511 A1, 1978 ;
