(1-溴甲基-乙烯基)-苯合成路线 （共 50 条）
反应条件
1: aqueous NaOH 2: SOCl2; pyridine; CHCl3 View Scheme
参考文献
Hatch; Patton
Journal of the American Chemical Society, 1954 , vol. 76, p. 2705
反应条件
1: 62 percent / 85percent H2O2, 1,3-dibromo-5,5-dimethylhydanthoin (DDH) / diethyl ether; H2O / 2 h / 0 °C 2: 48 percent / NaOH / CH2Cl2; H2O / 2 h / 0 °C View Scheme
参考文献
Adam, Waldemar; Heil, Markus
Chemische Berichte, 1992 , vol. 125, # 1 p. 235 - 241
反应条件
zinc in tetrahydrofuran 1.) reflux; 2.) 1 h, 50 deg C;
参考文献
Kopp, Michael; Krauth, Luise R.; Ratka, Richard; Weidenhammer, Klaus; Ziegler, Manfred L.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980 , vol. 35, # 7 p. 802 - 807
反应条件
di-tert-butyl peroxide; potassium carbonate
T=120°C; 93 h;
参考文献
Struss, John A.; Sadeghipour, Mitra; Tanko, James M.
Tetrahedron Letters, 2009 , vol. 50, # 18 p. 2119 - 2120
反应条件
in N,N-dimethyl-formamide
Ambient temperature;
参考文献
Abbenante, Giovanni; Prager, Rolf H.
Australian Journal of Chemistry, 1992 , vol. 45, # 11 p. 1791 - 1800
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
T=20°C; 20 h;
参考文献
Wei, Ying; Liang, Fushun; Zhang, Xintong
Organic Letters, 2013 , vol. 15, # 20 p. 5186 - 5189
反应条件
ammonia in methanol
T=130°C; 16 h;
参考文献
Van Hende, Eva; Verniest, Guido; Deroose, Frederik; Thuring, Jan-Willem; Macdonald, Gregor; De Kimpe, Norbert
Journal of Organic Chemistry, 2009 , vol. 74, # 5 p. 2250 - 2253
反应条件
zinc in tetrahydrofuran
1.) reflux; 2.) 1 h, 50 deg C;
参考文献
Kopp, Michael; Krauth, Luise R.; Ratka, Richard; Weidenhammer, Klaus; Ziegler, Manfred L.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980 , vol. 35, # 7 p. 802 - 807
反应条件
2-propenylmagnesium bromide
参考文献
Pines et al.
Journal of Organic Chemistry, 1957 , vol. 22, p. 1113
反应条件
1.1: n-BuLi / tetrahydrofuran; petroleum ether / 1.5 h / 20 °C
1.2: MgBr2 / tetrahydrofuran; petroleum ether / 0.5 h / 20 °C
1.3: tetrahydrofuran; petroleum ether / 20 °C
2.1: aq. NaOH / methanol; tetrahydrofuran
3.1: LiHMDS; t-BuOOLi / tetrahydrofuran; toluene / 2.5 h / -78 - 0 °C
3.2: 98 percent / tetrahydrofuran; toluene / -78 - 0 °C
View Scheme
参考文献
Zhang, Liming; Kozmin, Sergey A.
Journal of the American Chemical Society, 2004 , vol. 126, # 33 p. 10204 - 10205
