6-氯-1,2,3,4-四氢异喹啉合成路线 （共 11 条）
反应条件
hydrogen bromide in acetic acid
反应条件
diborane in tetrahydrofuran 2.5 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 23, # 5 p. 506 - 511
反应条件
hydrogenchloride in tert-butyl alcohol T=75°C; 10 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1977 - 1982
反应条件
1: 100 percent / benzene / Heating 2: concd. H2SO4 / 0.5 h / 140 - 150 °C 3: diborane / tetrahydrofuran / 2.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 23, # 5 p. 506 - 511
反应条件
1: concd. H2SO4 / 0.5 h / 140 - 150 °C 2: diborane / tetrahydrofuran / 2.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 23, # 5 p. 506 - 511
反应条件
1: H2SO4; AcOH / ethanol / 20 °C 2: HCl / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 1 p. 87 - 95
反应条件
1: LiAlH4 / diethyl ether / Heating 2: H2SO4; AcOH / ethanol / 20 °C 3: HCl / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 1 p. 87 - 95
反应条件
1: H2SO4; AcOH / ethanol / 20 °C 2: HCl / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 1 p. 87 - 95
反应条件
1: LiAlH4 / diethyl ether / Heating 2: H2SO4; AcOH / ethanol / 20 °C 3: HCl / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 10, # 1 p. 87 - 95
反应条件
1: NaBH4, SnCl4 2: 77 percent / potassium carbonate / H2O; toluene; benzene / 1.) 0 deg C, 30 min; 2.) 35 deg C, 24 h 3: methanesulphonic acid / acetic anhydride; 1,2-dichloro-ethane / 35 °C 4: 67 percent / methanesulphonic acid / acetic anhydride; 1,2-dichloro-ethane / 35 °C 5: aqueous HCl / 2-methyl-propan-2-ol / 10 h / 75 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1977 - 1982
