2,2′-二吡啶基 N-氧化物合成路线 （共 35 条）
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-70°C; Metallation; 0.5 h;
2: With iodine in tetrahydrofuran; hexane
T=-70°C; Iodination; 1 h;
参考文献
Trecourt, Francois; Gervais, Bruno; Mongin, Olivier; Gal, Catherine Le; Mongin, Florence; Queguiner, Guy
Journal of Organic Chemistry, 1998 , vol. 63, # 9 p. 2892 - 2897
反应条件
1: Ts2O / various solvent(s) / 0.25 h
2: TFA / various solvent(s) / 12 h / 70 °C
View Scheme
参考文献
Araki, Koji; Mutai, Toshiki; Shigemitsu, Yasuhiro; Yamada, Masaki; Nakajima, Takayoshi; et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1996 , # 4 p. 613 - 618
反应条件
1: benzoyl chloride / CH2Cl2 / Heating
2: 85 percent / g. H2S; triethylamine / ethanol
View Scheme
参考文献
Antonini, Ippolito; Claudi, Francesco; Cristalli, Gloria; Franchetti, Palmarisa; Grifantini, Mario; Martelli, Sante
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1181 - 1184
反应条件
1: 62.4 percent / benzoyl chloride / H2O / Ambient temperature
2: 79 percent / hydrogen sulfide / ethanol
View Scheme
参考文献
Antonini, Ippolito; Claudi, Francesco; Cristalli, Gloria; Franchetti, Palmarisa; Grifantini, Mario; Martelli, Sante
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1181 - 1184
反应条件
1: 62.4 percent / benzoyl chloride / H2O / Ambient temperature
2: 50 percent / hydrogen sulfide / ethanol
View Scheme
参考文献
Antonini, Ippolito; Claudi, Francesco; Cristalli, Gloria; Franchetti, Palmarisa; Grifantini, Mario; Martelli, Sante
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1181 - 1184
