8-DESOXYGARTANIN合成路线 （共 7 条）
反应条件
1: With potassium hydroxide in water T=10°C; 48 h; 2: With hydrogenchloride in water regioselective reaction;
参考文献
Zhang, Xiaojin; Li, Xiang; Tao, Lei; Gao, Yuan; Gong, Dandan; Xi, Meiyang; Xu, Xiaoli; Guo, Qinglong; You, Qidong; Ye, Suofu; Zhang, Yu; Meng, Huyan; Zhang, Mingqian; Gao, Wenlei
Medicinal Chemistry, 2012 , vol. 8, # 6 p. 1012 - 1025,14
反应条件
1: oxalyl chloride / CH2Cl2 / 3 h / 20 °C 2: 86 percent / AlCl3 / CH2Cl2 / 15 h / 20 °C 3: 93 percent / pyridine; aq. tetramethylammonium hydroxide / 4 h / Heating 4: 95 percent / aq. HI; phenol / 24 h / Heating 5: 10 percent / aq. KOH / 16 h / 20 °C View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
1: 86 percent / AlCl3 / CH2Cl2 / 15 h / 20 °C 2: 93 percent / pyridine; aq. tetramethylammonium hydroxide / 4 h / Heating 3: 95 percent / aq. HI; phenol / 24 h / Heating 4: 10 percent / aq. KOH / 16 h / 20 °C View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
potassium hydroxide T=20°C; 16 h;
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
1: trichlorophosphate; zinc(II) chloride / 3 h / 65 °C / |Inert atmosphere 2: potassium hydroxide / water / 48 h / 10 °C View Scheme
参考文献
Zhang, Xiaojin; Li, Xiang; Tao, Lei; Gao, Yuan; Gong, Dandan; Xi, Meiyang; Xu, Xiaoli; Guo, Qinglong; You, Qidong; Ye, Suofu; Zhang, Yu; Meng, Huyan; Zhang, Mingqian; Gao, Wenlei
Medicinal Chemistry, 2012 , vol. 8, # 6 p. 1012 - 1025,14
反应条件
1: 95 percent / aq. HI; phenol / 24 h / Heating 2: 10 percent / aq. KOH / 16 h / 20 °C View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
反应条件
1: 93 percent / pyridine; aq. tetramethylammonium hydroxide / 4 h / Heating 2: 95 percent / aq. HI; phenol / 24 h / Heating 3: 10 percent / aq. KOH / 16 h / 20 °C View Scheme
参考文献
Helesbeux, Jean-Jacques; Duval, Olivier; Dartiguelongue, Caroline; Seraphin, Denis; Oger, Jean-Michel; Richomme, Pascal
Tetrahedron, 2004 , vol. 60, # 10 p. 2293 - 2300
