1: KOH; water; iodine 2: concentrated sulfuric acid View Scheme

1: triethylamine / dichloromethane 2: isopropylmagnesium chloride / tetrahydrofuran 3: sodium iodide; chloro-trimethyl-silane / acetonitrile 4: dichloromethane 5: triethylamine / dichloromethane / 12 h / 0 - 20 °C / |Inert atmosphere 6: diisobutylaluminium hydride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 7: chloro-trimethyl-silane / dichloromethane / 9 h / 0 - 20 °C / |Inert atmosphere 8: isopropylmagnesium chloride lithium chloride complex / diethyl ether; tetrahydrofuran / 1.08 h / -78 - 0 °C / |Inert atmosphere 9: palladium 10 on activated carbon; potassium fluoride / methanol / 48 h / 70 °C / |Inert atmosphere; |Microwave irradiation 10: toluene-4-sulfonic acid / acetone / 9 h / 20 °C View Scheme

1: 64 percent / MeONa / dimethylformamide / Ambient temperature 2: Na2Se, NaBH4 / 4 h / Heating View Scheme

1: 64 percent / MeONa / dimethylformamide / Ambient temperature 2: Na2Se, NaBH4 / 4 h / Heating View Scheme

1: 64 percent / MeONa / dimethylformamide / Ambient temperature 2: Na2Te, NaBH4 / ethanol / 4 h / Heating View Scheme

sodium hydrogen telluride; acetic acid in ethanol 4 h; Heating;

sodium tetrahydroborate; acetic acid in ethanol

potassium carbonate in acetone 16 h; Heating;